Sifting through countless of stocks in the Biotechnology industry can be tedious, and sometimes two stocks are just too similar to judge which is the better investment. If you’re on the fence about investing in Alkermes plc or Fortrea Holdings Inc. because you’re not sure how they measure up, it’s important to compare them on a few factors before making your decision.

Read on to learn how Alkermes plc and Fortrea Holdings Inc. compare based on key financial metrics to determine which better meets your investment needs.

About Alkermes plc and Fortrea Holdings Inc.

Alkermes plc, a biopharmaceutical company, engages in the research, development, and commercialization of pharmaceutical products to address unmet medical needs of patients in therapeutic areas in the United States, Ireland, and internationally. The company has a portfolio of proprietary commercial products for the treatment of opioid dependence, alcohol dependence, schizophrenia, bipolar I, and a pipeline of clinical and preclinical product candidates in development for neurological disorders. Its marketed products include ARISTADA, an intramuscular injectable suspension for the treatment of schizophrenia; ARISTADA INITIO for the treatment of schizophrenia in adults; VIVITROL for the treatment of alcohol and prevention of opioid dependence; LYBALVI, an oral atypical antipsychotic drug candidate for the treatment of adults with schizophrenia and bipolar I disorder; and LUMRYZ, an extended-release oral suspension product for the treatment of cataplexy or EDS in pediatric patients. The company also offers proprietary technology platforms to third parties to enable them to develop, commercialize, and manufacture products. It has collaboration agreements primarily with Janssen Pharmaceutica N.V., Janssen Pharmaceutica Inc, and Janssen Pharmaceutica International. Alkermes plc was founded in 1987 and is headquartered in Dublin, Ireland.

Fortrea Holdings Inc., a contract research organization, provides biopharmaceutical product and medical device development solutions to pharmaceutical, biotechnology, and medical device customers worldwide. It offers clinical pharmacology, such as clinical research units, external partnerships, project management, study design and monitoring, bioanalytics and biomarkers, pharmacokinetics, modeling and simulation, and biometrics; and clinical development, including phase I through IV clinical and real-world evidence studies, regulatory affairs, protocol design, operational planning, study and site start-up, patient recruitment, project management, comprehensive site and medical monitoring, data management and biostatistics, pharmacovigilance, medical writing, and mobile clinical services. The company also provides consulting services comprising product development and regulatory, market access and health economics, and outcomes research, as well as RWE services. Fortrea Holdings Inc. was incorporated in 2023 and is headquartered in Durham, North Carolina.

Latest Biotechnology and Alkermes plc, Fortrea Holdings Inc. Stock News

As of July 31, 2026, Alkermes plc had a $8.2 billion market capitalization, compared to the Biotechnology median of $252.6 million. Alkermes plc’s stock is up 75.1% in 2026, down 7.4% in the previous five trading days and up 75.4% in the past year.

Currently, Alkermes plc’s price-earnings ratio is 126.3. Alkermes plc’s trailing 12-month revenue is $1.7 billion with a 4.0% net profit margin. Year-over-year quarterly sales growth most recently was 27.0%. Analysts expect adjusted earnings to reach $1.275 per share for the current fiscal year. Alkermes plc does not currently pay a dividend.

As of July 31, 2026, Fortrea Holdings Inc. had a $1.8 billion market cap, putting it in the 53rd percentile of all stocks. Fortrea Holdings Inc.’s stock is up 11.1% in 2026, down 1.8% in the previous five trading days and up 209.19% in the past year.

Currently, Fortrea Holdings Inc. does not have a price-earnings ratio. Fortrea Holdings Inc.’s trailing 12-month revenue is $2.7 billion with a -3.2% net profit margin. Year-over-year quarterly sales growth most recently was -4.5%. Analysts expect adjusted earnings to reach $0.845 per share for the current fiscal year. Fortrea Holdings Inc. does not currently pay a dividend.

How We Compare Alkermes plc and Fortrea Holdings Inc. Stock Grades

Stock evaluation requires access to huge amounts of data and the knowledge and time to sift through it all, make sense of financial ratios, read income statements and analyze recent stock movements. AAII created A+ Investor, a robust data suite that condenses data research in an actionable and customizable way suitable for investors of all knowledge levels, to help investors streamline and work through such data.

AAII’s proprietary stock grades come with A+ Investor. These offer intuitive A‐F grades for each of five key investing factors: value, growth, momentum, earnings estimate revisions and quality. Here, we’ll take a closer look at Alkermes plc and Fortrea Holdings Inc.’s stock grades to see how they measure up against one another.

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Alkermes plc and Fortrea Holdings Inc. Stock Value Grades

Company	Ticker	Value
Alkermes plc	ALKS	F
Fortrea Holdings Inc.	FTRE	C

Successful stock investing involves buying low and selling high, so stock valuation is an important consideration for stock selection.

Buying stocks that are going to go up typically means buying stocks that are undervalued in the first place, although momentum investors may argue that point.

AAII’s A+ Investor Value Grade derives from a stock’s value score. The Value Score is the percentile rank of the average of the percentile ranks of the price-to-sales ratio, price-earnings ratio, enterprise-value-to-EBITDA (EV/EBITDA) ratio, shareholder yield, price-to-book-value ratio and price-to-free-cash-flow ratio. The score is variable, meaning it can consider all six ratios or, should any of the six ratios not be valid, the remaining ratios that are valid. To be assigned a Value Score, stocks must have a valid (non-null) ratio and corresponding ranking for at least two of the six valuation ratios.

Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are a good value and so on.

Alkermes plc has a Value Score of 10, which is Ultra Expensive. Fortrea Holdings Inc. has a Value Score of 46, which is Average.

The Value Stock Winner: No Clear Winner

Neither Alkermes plc or Fortrea Holdings Inc. has a high enough value grade to be considered a “winner.” Investors who are considering these companies should do additional due diligence and research to see if either could be a good addition to their portfolio. It’s important to look at a wide range of financial metrics in order to determine if Alkermes plc or Fortrea Holdings Inc. is the better investment when it comes to value.

Alkermes plc and Fortrea Holdings Inc.’s Quality Grades

Company	Ticker	Quality
Alkermes plc	ALKS	C
Fortrea Holdings Inc.	FTRE	C

Like the Value Grade, AAII’s A+ Investor Quality Grade comes from the percentile rank of key metrics. Specifically, the Quality Score is the percentile rank of the average of the percentile ranks of return on assets (ROA), return on invested capital (ROIC), gross profit relative to assets, buyback yield, change in total liabilities to assets, accruals, Z double prime bankruptcy risk (Z) score and the F-Score.

The score is variable, meaning it can consider all eight measures or, should any of the eight measures not be valid, the remaining measures that are valid. To be assigned a Quality Score, stocks must have a valid (non-null) measure and corresponding ranking for at least four of the eight quality measures.

The Quality Score is used to assess the underlying “quality” of a particular stock. A higher-quality stock possesses traits associated with upside potential and reduced downside risk. Backtesting of the Quality Grade shows that stocks with higher grades, on average, outperformed stocks with lower grades over the period of 1998 through 2019.

Stocks receive better grades (higher scores) for having higher scores for the quality subcomponents and worse grades (lower scores) for lower scores for the subcomponents.

Alkermes plc has a Quality Score of 46, which is Average. Fortrea Holdings Inc. has a Quality Score of 57, which is Average.

The Quality Stock Winner: No Clear Winner

Neither Alkermes plc or Fortrea Holdings Inc. has a high enough Quality Grade to be considered a “winner.” Investors who are considering these companies should do additional due diligence and research to see if either could be a good addition to their portfolios. It’s important to look at a wide range of financial metrics in order to determine if Alkermes plc or Fortrea Holdings Inc. is the better investment when it comes to quality.

Alkermes plc and Fortrea Holdings Inc.’s Estimate Revisions Grades

Company	Ticker	Earnings Estimate
Alkermes plc	ALKS	B
Fortrea Holdings Inc.	FTRE	B

Earnings estimate revisions scores consider the magnitude of a company’s earnings surprise in its last two reported fiscal quarters. Often, positive surprises beget further positive surprises‐or at least continued sales growth (the exact opposite is generally true, too).

Estimate revisions offer an indication of what analysts are thinking about the short-term prospects of a firm. Estimate revisions are based on the statistical significance of a firm’s last two quarterly earnings surprises and the percentage change in its consensus estimate for the current fiscal year over the past month and past three months.

Alkermes plc has a Earnings Estimate Score of 73, which is Positive. Fortrea Holdings Inc. has a Earnings Estimate Score of 78, which is Positive.

The Earnings Estimate Revisions Grade Winner: It’s a Tie!

Looking at the Earnings Estimate Revisions Grade breakdown above, both Alkermes plc and Fortrea Holdings Inc. have a grade of B. For those focusing solely on a company’s estimate revisions, other financial metrics will need to be evaluated to determine whether Alkermes plc or Fortrea Holdings Inc. is a better fit.

Other Alkermes plc and Fortrea Holdings Inc. Grades

In addition to Estimate Revisions, Quality and Value, A+ Investor also provides grades for Growth and Momentum.

Momentum grades help uncover stocks experiencing anomalously high rates of return; research finds that stocks with high relative levels of momentum tend to outperform, whereas those with low levels of momentum tend to continue underperforming.

Growth investing builds on the idea that stocks of companies exhibiting strong, consistent and prolonged growth outperform those of slower-growth companies. AAII measures growth through consistency of annual sales growth, five-year sales growth rankings adjusted for extreme levels, and consistency of positive annual cash from operations.

These 2 key factors, when combined with the above, provide a holistic view into a particular stock. Further, by joining A+ Investor you can see whether Alkermes plc and Fortrea Holdings Inc. pass any of our 60+ stock screens that have outperformed the market since their creation.

So, Which Is the Better Investment, Alkermes plc or Fortrea Holdings Inc. Stock?

Overall, Alkermes plc stock has a Value Score of 10, Estimate Revisions Score of 73 and Quality Score of 46.

Fortrea Holdings Inc. stock has a Value Score of 46, Estimate Revisions Score of 78 and Quality Score of 57.

Comparing Alkermes plc and Fortrea Holdings Inc.’s grades, scores and metrics can act as a solid basis to determine whether they may be a good investment or not. You’ll also want to look at your portfolio’s asset allocation as well as your risk tolerance and financial goals to see if either of these stocks would make a good fit for you. AAII can help you figure out which investments align with your individual needs and preferences.

Investors are encouraged to do their own due diligence and research. In this way, individuals can effectively become managers of their own assets‐without having to rely on others for financial independence. You can count on AAII for timeless articles on financial planning and stock-picking, unbiased research and actionable analysis.

A+ Investor adds to our qualitative teaching with a powerful data suite to help you whittle down investment choices to find stocks, exchange-traded funds (ETFs) or mutual funds that meet your needs.

AAII Disclaimer

We make no representations or warranties that any investor will, or is likely to, achieve profits similar to those shown, because past, hypothetical or simulated performance is not necessarily indicative of future results. Before making an investment decision, you should consider your circumstances and whether the information on our content is applicable to your situation. This information was prepared in good faith, and we accept no liability for any errors or omissions. The full disclaimer can be read here.