Sifting through countless of stocks in the Biotechnology industry can be tedious, and sometimes two stocks are just too similar to judge which is the better investment. If you’re on the fence about investing in Legend Biotech Corporation, Xencor or Inc. because you’re not sure how they measure up, it’s important to compare them on a few factors before making your decision.

Read on to learn how Legend Biotech Corporation, Xencor and Inc. compare based on key financial metrics to determine which better meets your investment needs.

About Legend Biotech Corporation, Xencor and Inc.

Legend Biotech Corporation, through its subsidiaries, operates as a biopharmaceutical company that discovers, develops, manufactures, and commercializes novel cell therapies for oncology and other indications in the United States, China, and Europe. Its lead product candidate is ciltacabtagene autoleucel, or cilta-cel, which is a chimeric antigen receptor (CAR-T) therapy for the treatment of multiple myeloma (MM). The company also has a portfolio of earlier-stage autologous CAR-T product candidates targeting various cancers, including acute lymphoblastic leukemia, gastric cancer, esophageal cancer, pancreatic cancer, colorectal cancer, small cell lung cancer, and non-small cell lung cancer. In addition, it develops allogeneic gamma delta CAR-T and allogeneic CAR-NK product candidates targeting B-cell maturation antigen (BCMA) for MM, which are in investigator-initiated Phase 1 clinical trials in China. The company has a collaboration and license agreement with Janssen Biotech, Inc. for the development and commercialization of cilta-cel, as well as a license agreement with Novartis Pharma AG for the development, manufacture, and commercialization of CAR-T cell therapies targeting delta-like ligand protein 3. Legend Biotech Corporation was founded in 2014 and is headquartered in Somerset, New Jersey.

Xencor, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of engineered antibodies for the treatment of cancer and autoimmune diseases. The company provides Ultomiris to treat patients with atypical hemolytic uremic syndrome, generalized myasthenia gravis, and neuromyelitis optica spectrum disororder; and Monjuvi for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma. It also develops XmAb819, a bispecific antibody to treat renal cell carcinoma; XmAb541, which is in Phase I for the treatment of ovarian cancer; XmAb808, a bispecific antibody that binds to the broadly expressed tumor antigen; XmAb942, which is in clinical development for patients with Crohn’s disease and ulcerative colitis; Plamotamab, a bispecific T-cell, which is in Phase Ib study to treat rheumatoid arthritis; and XmAb657 for patients with idiopathic inflammatory myopathies. Further, the company develops Xaluritamig, a bispecific T-cell engager that treats prostate cancer; ASP2138 to treat gastric, gastroesophageal junction, and pancreatic cancers; JNJ-9401 to treat metastatic castration-resistant prostate cancer; Obexelimab, an antibody to treat patients with autoimmune diseases; Tobevibart, a treatment for chronic hepatitis Delta; Zaltenibart to treat paroxysmal nocturnal hemoglobinuria and other alternative pathway disorders; Teropavimab and zinlirvimab to treat human immunodeficiency virus; Novartis, an antibody drug candidate that uses XmAb Fc technologies; and JNJ-1493 to treat B-cell malignancies. The company was incorporated in 1997 and is headquartered in Pasadena, California.

Latest Biotechnology and Legend Biotech Corporation, Xencor, Inc. Stock News

As of August 20, 2026, Legend Biotech Corporation had a $4.1 billion market capitalization, compared to the Biotechnology median of $286.3 million. Legend Biotech Corporation’s stock is up 0.4% in 2026, up 7.1% in the previous five trading days and down 41.79% in the past year.

Currently, Legend Biotech Corporation does not have a price-earnings ratio. Legend Biotech Corporation’s trailing 12-month revenue is $1.1 billion with a -7.2% net profit margin. Year-over-year quarterly sales growth most recently was 56.5%. Analysts expect adjusted earnings to reach $-0.010 per share for the current fiscal year. Legend Biotech Corporation does not currently pay a dividend.

As of August 20, 2026, Xencor, Inc. had a $2.0 billion market cap, putting it in the 53rd percentile of all stocks. Xencor, Inc.’s stock is up 81.6% in 2026, up 19.1% in the previous five trading days and up 255.73% in the past year.

Currently, Xencor, Inc. does not have a price-earnings ratio. Xencor, Inc.’s trailing 12-month revenue is $105.0 million with a -155.6% net profit margin. Year-over-year quarterly sales growth most recently was 17.4%. Analysts expect adjusted earnings to reach $-3.114 per share for the current fiscal year. Xencor, Inc. does not currently pay a dividend.

How We Compare Legend Biotech Corporation, Xencor and Inc. Stock Grades

Stock evaluation requires access to huge amounts of data and the knowledge and time to sift through it all, make sense of financial ratios, read income statements and analyze recent stock movements. AAII created A+ Investor, a robust data suite that condenses data research in an actionable and customizable way suitable for investors of all knowledge levels, to help investors streamline and work through such data.

AAII’s proprietary stock grades come with A+ Investor. These offer intuitive A‐F grades for each of five key investing factors: value, growth, momentum, earnings estimate revisions and quality. Here, we’ll take a closer look at Legend Biotech Corporation, Xencor and Inc.’s stock grades to see how they measure up against one another.

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Legend Biotech Corporation, Xencor and Inc. Stock Value Grades

Company	Ticker	Value
Legend Biotech Corporation	LEGN	D
Xencor, Inc.	XNCR	F

Successful stock investing involves buying low and selling high, so stock valuation is an important consideration for stock selection.

Buying stocks that are going to go up typically means buying stocks that are undervalued in the first place, although momentum investors may argue that point.

AAII’s A+ Investor Value Grade derives from a stock’s value score. The Value Score is the percentile rank of the average of the percentile ranks of the price-to-sales ratio, price-earnings ratio, enterprise-value-to-EBITDA (EV/EBITDA) ratio, shareholder yield, price-to-book-value ratio and price-to-free-cash-flow ratio. The score is variable, meaning it can consider all six ratios or, should any of the six ratios not be valid, the remaining ratios that are valid. To be assigned a Value Score, stocks must have a valid (non-null) ratio and corresponding ranking for at least two of the six valuation ratios.

Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are a good value and so on.

Legend Biotech Corporation has a Value Score of 24, which is Expensive. Xencor, Inc. has a Value Score of 12, which is Ultra Expensive.

The Value Stock Winner: No Clear Winner

Neither Legend Biotech Corporation, Xencor or Inc. has a high enough value grade to be considered a “winner.” Investors who are considering these companies should do additional due diligence and research to see if either could be a good addition to their portfolio. It’s important to look at a wide range of financial metrics in order to determine if Legend Biotech Corporation, Xencor or Inc. is the better investment when it comes to value.

Legend Biotech Corporation, Xencor and Inc.’s Quality Grades

Company	Ticker	Quality
Legend Biotech Corporation	LEGN	C
Xencor, Inc.	XNCR	F

Like the Value Grade, AAII’s A+ Investor Quality Grade comes from the percentile rank of key metrics. Specifically, the Quality Score is the percentile rank of the average of the percentile ranks of return on assets (ROA), return on invested capital (ROIC), gross profit relative to assets, buyback yield, change in total liabilities to assets, accruals, Z double prime bankruptcy risk (Z) score and the F-Score.

The score is variable, meaning it can consider all eight measures or, should any of the eight measures not be valid, the remaining measures that are valid. To be assigned a Quality Score, stocks must have a valid (non-null) measure and corresponding ranking for at least four of the eight quality measures.

The Quality Score is used to assess the underlying “quality” of a particular stock. A higher-quality stock possesses traits associated with upside potential and reduced downside risk. Backtesting of the Quality Grade shows that stocks with higher grades, on average, outperformed stocks with lower grades over the period of 1998 through 2019.

Stocks receive better grades (higher scores) for having higher scores for the quality subcomponents and worse grades (lower scores) for lower scores for the subcomponents.

Legend Biotech Corporation has a Quality Score of 47, which is Average. Xencor, Inc. has a Quality Score of 11, which is Very Weak.

The Quality Stock Winner: No Clear Winner

Neither Legend Biotech Corporation, Xencor or Inc. has a high enough Quality Grade to be considered a “winner.” Investors who are considering these companies should do additional due diligence and research to see if either could be a good addition to their portfolios. It’s important to look at a wide range of financial metrics in order to determine if Legend Biotech Corporation, Xencor or Inc. is the better investment when it comes to quality.

Legend Biotech Corporation, Xencor and Inc.’s Momentum Grades

Company	Ticker	Momentum
Legend Biotech Corporation	LEGN	F
Xencor, Inc.	XNCR	A

Momentum grades help to uncover stocks experiencing anomalously high rates of return; research finds that stocks with high relative levels of momentum tend to outperform, whereas those with low levels of momentum tend to continue underperforming. Momentum is based on the price change of a stock over a specified period relative to all other stocks.

Typically, AAII looks at the weighted relative strength over the trailing four quarters. The weighted four-quarter relative strength rank is the relative price change for each of the past four quarters. The most recent quarterly price change is given a weight of 40% and each of the three previous quarters are given a weighting of 20%.

Legend Biotech Corporation has a Momentum Score of 16, which is Very Weak. Xencor, Inc. has a Momentum Score of 99, which is Very Strong.

The Momentum Grade Winner: Xencor, Inc.

As you can clearly see from the Momentum Grade breakdown above, Xencor, Inc. is considered to have stronger momentum compared to Legend Biotech Corporation. For those specifically looking for companies that have stronger momentum compared to other companies in the same industry, Xencor, Inc. could be a good stock to invest in. However, it’s important for investors to analyze multiple factors based on a wide range of metrics before deciding whether to buy.

Other Legend Biotech Corporation, Xencor and Inc. Grades

In addition to Value, Momentum and Quality, A+ Investor also provides grades for Growth and Estimate Revisions.

Earnings estimate revisions scores take into account the magnitude of a company’s earnings surprise in its last two reported fiscal quarters. Often, surprises beget further surprises‐or at least continued sales growth (the exact opposite is generally true, too).

Growth investing builds on the idea that stocks of companies exhibiting strong, consistent and prolonged growth outperform those of slower-growth companies. AAII measures growth through consistency of annual sales growth, five-year sales growth rankings adjusted for extreme levels, and consistency of positive annual cash from operations.

These 2 key factors, when combined with the above, provide a holistic view into a particular stock. Further, by joining A+ Investor you can see whether Legend Biotech Corporation, Xencor and Inc. pass any of our 60+ stock screens that have outperformed the market since their creation.

So, Which Is the Better Investment, Legend Biotech Corporation, Xencor or Inc. Stock?

Overall, Legend Biotech Corporation stock has a Value Score of 24, Momentum Score of 16 and Quality Score of 47.

Xencor, Inc. stock has a Value Score of 12, Momentum Score of 99 and Quality Score of 11.

Comparing Legend Biotech Corporation, Xencor and Inc.’s grades, scores and metrics can act as a solid basis to determine whether they may be a good investment or not. You’ll also want to look at your portfolio’s asset allocation as well as your risk tolerance and financial goals to see if either of these stocks would make a good fit for you. AAII can help you figure out which investments align with your individual needs and preferences.

Investors are encouraged to do their own due diligence and research. In this way, individuals can effectively become managers of their own assets‐without having to rely on others for financial independence. You can count on AAII for timeless articles on financial planning and stock-picking, unbiased research and actionable analysis.

A+ Investor adds to our qualitative teaching with a powerful data suite to help you whittle down investment choices to find stocks, exchange-traded funds (ETFs) or mutual funds that meet your needs.

AAII Disclaimer

We make no representations or warranties that any investor will, or is likely to, achieve profits similar to those shown, because past, hypothetical or simulated performance is not necessarily indicative of future results. Before making an investment decision, you should consider your circumstances and whether the information on our content is applicable to your situation. This information was prepared in good faith, and we accept no liability for any errors or omissions. The full disclaimer can be read here.