Stock Evaluator: Alnylam Pharmaceuticals, Inc. (ALNY)

Alnylam Pharmaceuticals, Inc. ALNY

$205.52 0.04 0.02%
July 31, 2026 4:00:00 PM EST November 10, 2021 Volume: 4,476,981
After Hours: $120.37   0.15  |  0.12% November 10, 2021 7:59 PM EST Volume: 72,713
USD NASD | DELAYED PRICE
SECTOR INDUSTRY
Health Care Biotechnology

A+ Stock Grade Summary:

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COMPANY SUMMARY
Alnylam Pharmaceuticals, Inc. discovers, develops, manufactures, and commercializes therapeutics based on ribonucleic acid interference in the United States, Europe, and internationally. The company offers ONPATTRO for hereditary transthyretin-mediated (hATTR) amyloidosis; AMVUTTRA for ATTR and hATTR amyloidosis; Leqvio for hypercholesterolemia; Qfitlia for hemophilia A or B; GIVLAARI for acute hepatic porphyria; and OXLUMO for primary hyperoxaluria type 1. It also develops a range of products in Phase 3 trial, such as Nucresiran for ATTR amyloidosis; Zilebesiran for hypertension; Cemdisiran for myasthenia gravis, paroxysmal nocturnal hemoglobinuria, and geographic atrophy; and Elebsiran for hepatitis D virus infections. In addition, the company is developing various products in Phase 2 trial, including Rapirosiran for metabolic dysfunction-associated steatohepatitis; ALN-ANG3 for diabetic kidney disease; ALN-4324 for type 2 diabetes mellitus; Mivelsiran for cerebral amyloid angiopathy, as well as in Phase 1 trial for Alzheimer’s disease; and ALN-6400 for bleeding disorders. Further, it develops a range of products in Phase 1 trial, such as ALN-2232 for obesity and weight management; ALN-PNP for non-alcoholic fatty liver disease; ALN-APOC3 for dyslipidemia; ALN-CIDEB for metabolic dysfunction-associated steatohepatitis; ALN-HTT02 for Huntington’s disease; ALN-5288 for Alzheimer’s disease; ALN-SOD for SOD1 amyotrophic lateral sclerosis; ALN-SNCA for Parkinson’s disease; AG-236 for polycythemia vera; ALN-CFB for paroxysmal nocturnal hemoglobinuria; ALN-BCAT for hepatocellular carcinoma; and ALN-4285, ALN-4915, and ALN-F1202 for healthy volunteers. The company has collaborations with Regeneron Pharmaceuticals, Inc.; Roche Holding AG; Sanofi S.A.; Novartis AG; PeptiDream, Inc; Dicerna Pharmaceuticals, Inc.; and Ionis Pharmaceuticals, Inc. Alnylam Pharmaceuticals, Inc. was founded in 2002 and is headquartered in Cambridge, Massachusetts.

Commentary & Analysis


Financial Summary

Share Statistics ALNY Industry
Median
Percentile
(All Stocks)
Market Cap (Mil) $27,500.4 $252.6 89%
Shares Out (Mil) 138.3 52.3 69%
Institutional Ownership 99.6% 92.1% 91%
Float (Mil) 132.9 40.2 67%
Beta 0.27 0.95 16%
Avg Daily Volume (000s) 2,419 455 85%
Price Change
(52-week)
(39.5%) 52.9% 20%
Growth ALNY Industry
Median
Percentile
(All Stocks)
Sales (5yr) 49.8% 13.6% 96%
Net Income (5yr) 18.8% (9.9%) 71%
EPS (5yr) 18.3% 16.0% 65
Dividends (5yr) 0.0% 0.0% 0%
Cash Flow (5yr) 69.5% (15.6%) 97%
Estimates Qtrly Current
Fiscal
Year
Next
Fiscal
Year
# of Estimates 11 13 15
Current EPS $2.197 $9.041 $13.114
Month Ago EPS $2.435 $9.421 $13.574
# Rev Up 1 1 1
# Rev Down 0 0 0
Three Months Ago EPS $2.384 $9.269 $13.961
Year/Year Chg 81.6% 288.0% 610.0%
Financials ALNY Industry
Median
Percentile
(All Stocks)
Sales (TTM) (Mil) $4,804 $38 74%
Net Income (TTM) (Mil) $775 ($43) 84%
EPS (TTM) $5.845 ($1.600) 89%
Operating Cash Flow (TTM) (Mil) $912 ($31) 80%
Net Cash Flow (TTM) (Mil) $594 $5 92%
Long-Term Debt (Q1) (Mil) $2,683 $5 78%
Enterprise Value (Q1) (Mil) $37,947 $180 90%
Valuation ALNY Industry
Median
Percentile
(All Stocks)
P/B 20.29 2.56 96%
P/E 36.6 19.0 75%
Dividend Yield 0.0% 0.0% 0%
PEG (5yr hist) 2.0 0.9 67%
Ratios ALNY Industry
Median
Percentile
(All Stocks)
Gross Margin 79.7% 63.8% 89%
Net Margin 16.1% (67.3%) 75%
ROA 15.3% (49.8%) 94%
ROE 96.6% (55.5%) 96%
Liabilities to Assets 75.6% 30.3% 71%
F-Score 7 3 84%

Alnylam Pharmaceuticals, Inc. did not pass any screens on 7/31/2026.

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