Stock Evaluator: Alto Neuroscience, Inc. (ANRO)

Alto Neuroscience, Inc. ANRO

$34.89 0.76 2.23%
August 19, 2026 4:00:02 PM EST November 10, 2021 Volume: 335,675
After Hours: $120.37   0.15  |  0.12% November 10, 2021 7:59 PM EST Volume: 72,713
USD NYSE | DELAYED PRICE
SECTOR INDUSTRY
Health Care Pharmaceuticals

A+ Stock Grade Summary:

VALUE:
GROWTH:
MOMENTUM:
EPS REVISIONS:
QUALITY:
COMPANY SUMMARY
Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States. The company’s product pipeline includes ALTO-100, which is in Phase 2b clinical trial for the treatment of patients with bipolar depression (BPD). It also develops ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties, which is in Phase 2b clinical trial to treat patients with major depressive disorder (MDD); ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor that is in Phase 2 proof-of-concept (POC) trial for the treatment of cognitive impairment associated with schizophrenia; ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist, which is in Phase 2 POC trial to treat patients with MDD and higher levels of anhedonia; ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor that is in Phase 1 clinical trial for the treatment of MDD; and ALTO-208, a fixed-dose combination of pramipexole and aprepitant, an antiemetic, neurokinin-1 (NK-1) receptor antagonist for patients with Parkinson’s disease for patients with Parkinson’s disease. The company was incorporated in 2019 and is headquartered in Mountain View, California.

Commentary & Analysis


Financial Summary

Share Statistics ANRO Industry
Median
Percentile
(All Stocks)
Market Cap (Mil) $1,344.0 $618.0 48%
Shares Out (Mil) 42.8 44.8 44%
Institutional Ownership 95.9% 85.3% 68%
Float (Mil) 29.7 47.4 36%
Beta 1.09 0.70 66%
Avg Daily Volume (000s) 507 390 58%
Price Change
(52-week)
898.5% 68.6% 100%
Growth ANRO Industry
Median
Percentile
(All Stocks)
Sales (5yr) na 6.7% na
Net Income (5yr) na (1.6%) na
EPS (5yr) na 14.9% na
Dividends (5yr) na 0.0% na
Cash Flow (5yr) na (14.9%) na
Estimates Qtrly Current
Fiscal
Year
Next
Fiscal
Year
# of Estimates 7 6 7
Current EPS ($0.703) ($2.922) ($3.286)
Month Ago EPS ($0.798) ($3.145) ($3.433)
# Rev Up 0 1 1
# Rev Down 0 0 0
Three Months Ago EPS ($0.810) ($3.135) ($3.165)
Year/Year Chg 8.8% 33.3% 53.5%
Financials ANRO Industry
Median
Percentile
(All Stocks)
Sales (TTM) (Mil) na $291 na
Net Income (TTM) (Mil) ($84) ($11) 12%
EPS (TTM) ($2.379) ($0.700) 13%
Operating Cash Flow (TTM) (Mil) ($68) ($6) 8%
Net Cash Flow (TTM) (Mil) $96 $5 77%
Long-Term Debt (Q1) (Mil) $18 $6 32%
Enterprise Value (Q1) (Mil) $1,041 $450 41%
Valuation ANRO Industry
Median
Percentile
(All Stocks)
P/B 5.48 2.78 80%
P/E na 17.4 na
Dividend Yield na 0.0% na
PEG (5yr hist) na 1.1 na
Ratios ANRO Industry
Median
Percentile
(All Stocks)
Gross Margin na 67.0% na
Net Margin na (2.3%) na
ROA (40.9%) (22.4%) 13%
ROE (49.2%) (20.2%) 15%
Liabilities to Assets 13.7% 32.2% 8%
F-Score 2 3 7%

Passing Stock Screens

As of 8/20/2026, from a list of 60 stock screening strategies, ANRO meetings the criteria of 1 screen:

Price and market data provided by QuoteMedia and delayed a minimum of 15 minutes unless otherwise indicated. Fundamental data provided by AAII's Stock Investor Pro and S&P Global Market Intelligence and are updated through the previous trading day.

Ⓒ 2026 American Association of Individual Investors