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Ensysce Biosciences, Inc., a clinical-stage pharmaceutical company, develops prescription drugs for severe pain relief in opioid misuse, abuse, and overdose in the United States. It develops products using Trypsin Activated Abuse Protection (TAAP) platform, designed to release clinically effective drugs only when exposed to specific physiological conditions; and Multi-Pill Abuse Resistance (MPAR) platform, an over-dose protection opioid prodrug technology. The company’s lead product candidate is PF614, a TAAP oxycodone prodrug candidate for the treatment of severe or chronic pain; and PF614-MPAR, a combination product of PF614 and nafamostat for overdose protection. It is also developing PF8001 and PF8026 are extended and immediate-release prodrugs of amphetamine for attention deficit hyperactivity disorder; and PF9001 to treat opioid use disorder. Ensysce Biosciences, Inc. was founded in 2003 and is based in La Jolla, California.
Learn more about Ensysce Biosciences Inc's (ENSC) stock grades for Momentum, Growth and Estimate Revisions and determine whether this Biotechnology & Medical Research stock meets your investment needs.
Jack Gilleland
Financial Summary
Share Statistics
ENSC
Industry Median
Percentile (All Stocks)
Market Cap (Mil)
$8.9
$282.4
6%
Shares Out (Mil)
13.0
54.0
24%
Institutional Ownership
58.9%
93.1%
38%
Float (Mil)
18.5
42.2
28%
Beta
0.90
0.94
54%
Avg Daily Volume (000s)
758
482
67%
Price Change (52-week)
(78.8%)
59.9%
7%
Growth
ENSC
Industry Median
Percentile (All Stocks)
Sales (5yr)
5.5%
14.1%
39%
Net Income (5yr)
(153.2%)
(10.1%)
1%
EPS (5yr)
na
15.9%
na
Dividends (5yr)
0.0%
0.0%
0%
Cash Flow (5yr)
na
(15.6%)
na
Estimates
Qtrly
Current Fiscal Year
Next Fiscal Year
# of Estimates
na
na
1
Current EPS
($0.190)
($1.090)
($0.050)
Month Ago EPS
$0.090
na
($0.110)
# Rev Up
1
0
na
# Rev Down
0
1
na
Three Months Ago EPS
na
na
na
Year/Year Chg
(3.6%)
(72.6%)
na
Financials
ENSC
Industry Median
Percentile (All Stocks)
Sales (TTM) (Mil)
$5
$37
5%
Net Income (TTM) (Mil)
($13)
($43)
27%
EPS (TTM)
($1.903)
($1.500)
15%
Operating Cash Flow (TTM) (Mil)
($9)
($31)
21%
Net Cash Flow (TTM) (Mil)
na
$2
na
Long-Term Debt (Q1) (Mil)
$0
$4
0%
Enterprise Value (Q1) (Mil)
$7
$190
6%
Valuation
ENSC
Industry Median
Percentile (All Stocks)
P/B
na
2.84
na
P/E
na
20.2
na
Dividend Yield
0.0%
0.0%
0%
PEG (5yr hist)
na
1.0
na
Ratios
ENSC
Industry Median
Percentile (All Stocks)
Gross Margin
(175.2%)
66.9%
1%
Net Margin
(280.5%)
(74.2%)
3%
ROA
(295.9%)
(47.7%)
1%
ROE
(968.3%)
(55.0%)
0%
Liabilities to Assets
137.6%
29.8%
97%
F-Score
1
3
1%
Ensysce Biosciences, Inc. did not pass any screens on 9/4/2026.
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Ⓒ 2026 American Association of Individual Investors