Stock Evaluator: Praxis Precision Medicines, Inc. (PRAX)

Praxis Precision Medicines, Inc. PRAX

$375.94 11.36 3.12%
August 21, 2026 3:59:59 PM EST November 10, 2021 Volume: 413,316
After Hours: $120.37   0.15  |  0.12% November 10, 2021 7:59 PM EST Volume: 72,713
USD NASD | DELAYED PRICE
SECTOR INDUSTRY
Health Care Biotechnology

A+ Stock Grade Summary:

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COMPANY SUMMARY
Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance in the United States. The company’s platforms include Cerebrum, a small molecule platform for CNS small molecule therapies to develop orally available precision therapies; and Solidus to discover and develop antisense oligonucleotide. It also develops ulixacaltamide, a small molecule inhibitor of T-type calcium channels that in NDA for the treatment of essential tremor; relutrigine, a small molecule, which is in NDA for the treatment of SCN2A- and SCN8A-developmental and epileptic encephalopathies (DEE), as well as in Phase 3 trial for broad DEEs; vormatrigine, a small molecule targeting the hyperexcitable state of sodium-channels in the brain that is in Phase 3 trial for the treatment of adjunctive focal epilepsy, as well as in Phase 2 trial for monotherapy focal epilepsy; and Elsunersen, a clinical-stage ASO designed to selectively decrease SCN2A gene expression, which is in Phase 3 trial for the treatment of SCN2A-DEE. In addition, the company is developing product candidates in pre-clinical trial comprising PRAX-020 to treat KCNT1; PRAX-080 that targets PCDH19 mosaic expression disorders; PRAX-090 for targeting SYNGAP1 loss-of-function; and PRAX-100 that targets SCN2A LoF mutations. It has a cooperation and license agreement with RogCon Inc.; research collaboration, option, and license agreement with Ionis Pharmaceuticals, Inc.; and research collaboration and license agreement to develop an iontophoretic transdermal patch for the delivery of ulixacaltamide. The company was formerly known as EpiPM Therapeutics, Inc. and changed its name to Praxis Precision Medicines, Inc. in October 2016. Praxis Precision Medicines, Inc. was incorporated in 2015 and is headquartered in Boston, Massachusetts.

Commentary & Analysis


Financial Summary

Share Statistics PRAX Industry
Median
Percentile
(All Stocks)
Market Cap (Mil) $10,493.5 $292.6 78%
Shares Out (Mil) 29.1 54.4 36%
Institutional Ownership 99.8% 93.2% 94%
Float (Mil) 24.1 40.2 32%
Beta na 0.94 na
Avg Daily Volume (000s) 413 544 55%
Price Change
(52-week)
730.6% 59.7% 100%
Growth PRAX Industry
Median
Percentile
(All Stocks)
Sales (5yr) na 13.6% na
Net Income (5yr) (37.5%) (10.1%) 10%
EPS (5yr) 35.2% 16.0% 85
Dividends (5yr) na 0.0% na
Cash Flow (5yr) (56.9%) (15.6%) 5%
Estimates Qtrly Current
Fiscal
Year
Next
Fiscal
Year
# of Estimates 17 17 16
Current EPS ($3.632) ($13.935) ($9.294)
Month Ago EPS ($4.026) ($15.323) ($9.656)
# Rev Up 0 2 0
# Rev Down 1 0 1
Three Months Ago EPS ($4.001) ($15.109) ($9.851)
Year/Year Chg 26.4% 3.4% (160.7%)
Financials PRAX Industry
Median
Percentile
(All Stocks)
Sales (TTM) (Mil) na $37 na
Net Income (TTM) (Mil) ($339) ($43) 4%
EPS (TTM) ($12.858) ($1.400) 3%
Operating Cash Flow (TTM) (Mil) ($305) ($31) 3%
Net Cash Flow (TTM) (Mil) $317 $2 88%
Long-Term Debt (Q1) (Mil) $0 $4 0%
Enterprise Value (Q1) (Mil) na $164 na
Valuation PRAX Industry
Median
Percentile
(All Stocks)
P/B 7.82 2.83 86%
P/E na 19.6 na
Dividend Yield na 0.0% na
PEG (5yr hist) na 1.0 na
Ratios PRAX Industry
Median
Percentile
(All Stocks)
Gross Margin na 64.2% na
Net Margin na (75.9%) na
ROA (36.8%) (47.5%) 15%
ROE (38.9%) (55.0%) 18%
Liabilities to Assets 3.5% 29.6% 1%
F-Score 3 3 18%

Praxis Precision Medicines, Inc. did not pass any screens on 8/21/2026.

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