Stock Evaluator: Sionna Therapeutics, Inc. (SION)

Sionna Therapeutics, Inc. SION

$47.13 0.35 0.75%
July 31, 2026 4:00:00 PM EST November 10, 2021 Volume: 390,673
After Hours: $120.37   0.15  |  0.12% November 10, 2021 7:59 PM EST Volume: 72,713
USD NASD | DELAYED PRICE
SECTOR INDUSTRY
Health Care Biotechnology

A+ Stock Grade Summary:

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COMPANY SUMMARY
Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial; navocaftor (SION-3067), a potentiator that has completed Phase 2 trial; SION-109, an intracellular loop 4 directed CFTR corrector that has completed Phase 1 trial; SION-2851, a TMD1-directed CFTR corrector that has completed Phase 1 trial; SION-451, which is nucleotide-binding domain 1 stabilizer in Phase 1 trial; and SION-719, which is nucleotide-binding domain 1 stabilizer in Phase 2a proof-of-concept trial. The company was formerly known as Sling Therapeutics, Inc. and changed its name to Sionna Therapeutics, Inc. in July 2021. Sionna Therapeutics, Inc. was incorporated in 2019 and is headquartered in Waltham, Massachusetts.

Commentary & Analysis


Financial Summary

Share Statistics SION Industry
Median
Percentile
(All Stocks)
Market Cap (Mil) $2,127.9 $252.6 55%
Shares Out (Mil) 44.9 52.3 45%
Institutional Ownership 96.8% 92.1% 71%
Float (Mil) 16.8 40.2 26%
Beta na 0.95 na
Avg Daily Volume (000s) 528 455 60%
Price Change
(52-week)
165.5% 52.9% 96%
Growth SION Industry
Median
Percentile
(All Stocks)
Sales (5yr) na 13.6% na
Net Income (5yr) na (9.9%) na
EPS (5yr) na 16.0% na
Dividends (5yr) na 0.0% na
Cash Flow (5yr) na (15.6%) na
Estimates Qtrly Current
Fiscal
Year
Next
Fiscal
Year
# of Estimates 9 9 9
Current EPS ($0.640) ($2.544) ($2.802)
Month Ago EPS ($0.640) ($2.544) ($2.802)
# Rev Up 0 2 1
# Rev Down 1 0 0
Three Months Ago EPS ($0.531) ($2.209) ($2.581)
Year/Year Chg 7.4% 35.1% 72.8%
Financials SION Industry
Median
Percentile
(All Stocks)
Sales (TTM) (Mil) na $38 na
Net Income (TTM) (Mil) ($86) ($43) 12%
EPS (TTM) ($1.921) ($1.600) 15%
Operating Cash Flow (TTM) (Mil) ($72) ($31) 7%
Net Cash Flow (TTM) (Mil) ($19) $5 26%
Long-Term Debt (Q1) (Mil) $7 $5 26%
Enterprise Value (Q1) (Mil) $1,665 $180 47%
Valuation SION Industry
Median
Percentile
(All Stocks)
P/B 7.38 2.56 86%
P/E na 19.0 na
Dividend Yield na 0.0% na
PEG (5yr hist) na 0.9 na
Ratios SION Industry
Median
Percentile
(All Stocks)
Gross Margin na 63.8% na
Net Margin na (67.3%) na
ROA (25.4%) (49.8%) 19%
ROE (26.7%) (55.5%) 21%
Liabilities to Assets 5.5% 30.3% 3%
F-Score 1 3 1%

Sionna Therapeutics, Inc. did not pass any screens on 7/31/2026.

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