Stock Evaluator: Senti Biosciences Holdings, Inc. (SNTI)

Senti Biosciences Holdings, Inc. SNTI

$0.34 -0.02 -5.52%
July 31, 2026 4:00:00 PM EST November 10, 2021 Volume: 148,855
After Hours: $120.37   0.15  |  0.12% November 10, 2021 7:59 PM EST Volume: 72,713
USD NASD | DELAYED PRICE
SECTOR INDUSTRY
Health Care Biotechnology

A+ Stock Grade Summary:

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COMPANY SUMMARY
Senti Biosciences Holdings, Inc., a clinical stage biotechnology company, develops cell and gene therapies engineered with its gene circuit platform technologies for patients living with incurable diseases. The company’s lead product candidates utilize off-the-shelf healthy adult donor derived natural killer (NK) cells to create CAR-NK cells outfitted with gene circuit technologies in various oncology indications with unmet need. It offers SENTI-202, a logic gated off-the-shelf CAR-NK cell therapy for the treatment of blood cancers and relapsed/refractory hematological malignancies, including acute myeloid leukemia. In addition, the company develops the tumor-associated antigen and protective antigen paired discovery platform to select and validate NOT GATE antigen candidates and identify tumor-associated antigens in cancer cells. Further, its pipeline includes preclinical programs, which comprise a solid tumor cell therapy program; and partnered programs related to cell therapies for regenerative medicines. The company has a strategic collaboration with Celest Therapeutics (Shanghai) Co. Ltd. The company was formerly known as Senti Biosciences, Inc. and changed its name to Senti Biosciences Holdings, Inc. in April 2026. The company was incorporated in 2016 and is headquartered in South San Francisco, California.

Commentary & Analysis


Financial Summary

Share Statistics SNTI Industry
Median
Percentile
(All Stocks)
Market Cap (Mil) $11.2 $251.9 7%
Shares Out (Mil) 31.0 50.8 38%
Institutional Ownership 83.0% 92.0% 51%
Float (Mil) 12.3 40.5 22%
Beta 2.05 0.95 93%
Avg Daily Volume (000s) 276 447 50%
Price Change
(52-week)
(80.0%) 54.2% 7%
Growth SNTI Industry
Median
Percentile
(All Stocks)
Sales (5yr) na 14.0% na
Net Income (5yr) (25.3%) (9.8%) 16%
EPS (5yr) 28.2% 16.3% 79
Dividends (5yr) 0.0% 0.0% 0%
Cash Flow (5yr) (15.8%) (15.6%) 46%
Estimates Qtrly Current
Fiscal
Year
Next
Fiscal
Year
# of Estimates 3 3 2
Current EPS ($0.317) ($1.157) ($0.950)
Month Ago EPS ($0.317) ($1.157) ($0.950)
# Rev Up 0 1 1
# Rev Down 0 0 0
Three Months Ago EPS ($0.277) ($1.093) ($0.895)
Year/Year Chg 133.1% (57.7%) (57.4%)
Financials SNTI Industry
Median
Percentile
(All Stocks)
Sales (TTM) (Mil) na $39 na
Net Income (TTM) (Mil) ($52) ($43) 16%
EPS (TTM) ($1.859) ($1.600) 16%
Operating Cash Flow (TTM) (Mil) ($37) ($30) 11%
Net Cash Flow (TTM) (Mil) ($25) $3 25%
Long-Term Debt (Q1) (Mil) $13 $5 30%
Enterprise Value (Q1) (Mil) $40 $182 15%
Valuation SNTI Industry
Median
Percentile
(All Stocks)
P/B 4.50 2.60 76%
P/E na 18.6 na
Dividend Yield 0.0% 0.0% 0%
PEG (5yr hist) na 0.9 na
Ratios SNTI Industry
Median
Percentile
(All Stocks)
Gross Margin na 63.8% na
Net Margin na (64.7%) na
ROA (85.2%) (49.7%) 7%
ROE (255.0%) (55.4%) 3%
Liabilities to Assets 93.3% 30.3% 91%
F-Score 2 3 7%

Senti Biosciences Holdings, Inc. did not pass any screens on 7/30/2026.

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