Stock Evaluator: Spruce Biosciences, Inc. (SPRB)

Spruce Biosciences, Inc. SPRB

$42.83 -0.54 -1.25%
July 31, 2026 4:00:00 PM EST November 10, 2021 Volume: 23,403
After Hours: $120.37   0.15  |  0.12% November 10, 2021 7:59 PM EST Volume: 72,713
USD NASD | DELAYED PRICE
SECTOR INDUSTRY
Health Care Biotechnology

A+ Stock Grade Summary:

VALUE:
GROWTH:
MOMENTUM:
EPS REVISIONS:
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COMPANY SUMMARY
Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, including anhedonia, weight alterations, and altered sleeping patterns. In addition, the company develops SPR202 for the treatment of Congenital Adrenal Hyperplasia (CAH), a chronic and potentially life-threatening rare disease with no cure. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize various pharmaceutical compounds. It also has a collaboration and license agreement with Kaken Pharmaceutical Co. Ltd. to develop, manufacture, and commercialize Tildacerfont for the treatment of CAH in Japan. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in South San Francisco, California.

Commentary & Analysis


Financial Summary

Share Statistics SPRB Industry
Median
Percentile
(All Stocks)
Market Cap (Mil) $117.9 $252.6 23%
Shares Out (Mil) 1.4 52.3 5%
Institutional Ownership 91.1% 92.1% 59%
Float (Mil) 2.4 40.2 6%
Beta 3.20 0.95 98%
Avg Daily Volume (000s) 52 455 29%
Price Change
(52-week)
423.9% 52.9% 99%
Growth SPRB Industry
Median
Percentile
(All Stocks)
Sales (5yr) na 13.6% na
Net Income (5yr) (5.7%) (9.9%) 33%
EPS (5yr) 32.8% 16.0% 83
Dividends (5yr) na 0.0% na
Cash Flow (5yr) (63.0%) (15.6%) 3%
Estimates Qtrly Current
Fiscal
Year
Next
Fiscal
Year
# of Estimates 7 7 7
Current EPS ($5.929) ($24.886) $7.384
Month Ago EPS ($6.242) ($25.635) $4.950
# Rev Up 3 0 0
# Rev Down 1 1 1
Three Months Ago EPS ($5.723) ($24.533) $4.300
Year/Year Chg (33.7%) (51.0%) (84.2%)
Financials SPRB Industry
Median
Percentile
(All Stocks)
Sales (TTM) (Mil) na $38 na
Net Income (TTM) (Mil) ($37) ($43) 19%
EPS (TTM) ($38.617) ($1.600) 2%
Operating Cash Flow (TTM) (Mil) ($29) ($31) 12%
Net Cash Flow (TTM) (Mil) na $5 na
Long-Term Debt (Q1) (Mil) $6 $5 25%
Enterprise Value (Q1) (Mil) $89 $180 20%
Valuation SPRB Industry
Median
Percentile
(All Stocks)
P/B 1.70 2.56 45%
P/E na 19.0 na
Dividend Yield na 0.0% na
PEG (5yr hist) na 0.9 na
Ratios SPRB Industry
Median
Percentile
(All Stocks)
Gross Margin na 63.8% na
Net Margin na (67.3%) na
ROA (84.7%) (49.8%) 7%
ROE (148.8%) (55.5%) 6%
Liabilities to Assets 38.3% 30.3% 29%
F-Score 3 3 19%

Spruce Biosciences, Inc. did not pass any screens on 7/31/2026.

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