Based on key financial metrics such as the price-to-sales ratio, shareholder yield and the price-earnings ratio, the following 7 stocks made the list for top value stocks in the Biotechnology & Medical Research industry. Those looking for value stocks to add to their portfolio may want to use this list as a starting point for further investment research.
Why Focus on Undervalued Biotechnology & Medical Research Stocks?
Value investors seek to buy stocks at a discount to their intrinsic value. Long-term returns show that such strategies are advantageous. Value stocks, as a group, tend to outperform growth stocks over extended periods of time. Typically, value investors perform financial analysis of numerous metrics, don’t follow the herd and are long-term investors.
AAII’s A+ Investor Value Grade is derived from a stock’s Value Score. The Value Score is the percentile rank of the average of the percentile ranks of the price-to-sales ratio, price-earnings ratio, enterprise-value-to-EBITDA (EV/EBITDA) ratio, shareholder yield, price-to-book-value ratio and price-to-free-cash-flow ratio. The score is variable, meaning it can consider all six ratios or, should any of the six ratios not be valid, the remaining ratios that are valid. To be assigned a Value Score, stocks must have a valid (non-null) ratio and corresponding ranking for at least two of the six valuation ratios.
What Goes Into AAII’s Value Grade?
Stock evaluation requires access to huge amounts of data as well as the knowledge and time to sift through it all, make sense of financial ratios, read income statements and analyze recent stock movement. AAII created A+ Investor, a robust data suite that condenses data research in an actionable and customizable way suitable for investors of all knowledge levels, to help investors with that task.
AAII’s proprietary stock grades come with A+ Investor. These offer intuitive A–F grades for more than just value. It is possible for a stock to appear cheap based on one valuation metric but appear expensive on another. It is also possible for one valuation ratio to be associated with outperforming stocks during certain periods of time but not others. Some stocks may even have null values for certain metrics like the price-earnings ratio or the price-to-book ratio but not others. An example of this would be a company with losses instead of profits or a negative book value because of heavy borrowing. Negative earnings or book value result in non-meaningful ratios that are left blank or null.
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7 Undervalued Biotechnology & Medical Research Stocks
Of course, there are countless value stocks that are worth mentioning, but this is a concise list of the top 7 undervalued stocks in the Biotechnology & Medical Research industry for Tuesday, May 28, 2024. Let’s take a closer look at their individual scores to see how they measure up against each other and the Biotechnology & Medical Research industry median.
| Company | Ticker | Price/Sales | Price/Earnings | EV/EBITDA | Shareholder Yield | Price/Book Value | Price/Free Cash Flow | Value Grade |
| Aditxt Inc | ADTX | 0.37 | na | na | (605.7%) | 0.09 | na | B |
| Creative Medical Technology Holdings Inc | CELZ | na | na | 0.3 | (1.4%) | 0.67 | na | A |
| Genprex Inc | GNPX | na | na | 0.1 | (30.8%) | 0.41 | na | B |
| Histogen Inc | HSTO | na | na | 0.2 | (20.2%) | 0.13 | na | A |
| Palisade Bio Inc | PALI | na | na | 0.5 | (167.0%) | 0.37 | na | B |
| Tenax Therapeutics Inc | TENX | na | na | 0.7 | (948.2%) | 0.34 | na | B |
| Exicure Inc | XCUR | 0.13 | 0.2 | 0.8 | (74.3%) | 0.63 | na | A |
The Value Grade is assigned based on how each stock’s composite valuation compares to all other stocks.
The process for assigning grades starts with each variable for a given stock. The percentile rankings for all valid ratios that a stock has are calculated. So, for instance, a stock could have a price-to-book ranking in the 43rd percentile, a price-earnings ranking in the 67th percentile, a price-to-sales ranking in the 23rd percentile, etc. Then, those rankings are averaged for each stock. (A minimum of two valid variables are required, though all six will be used if available.)
Once the average of the individual variables is calculated, that average is ranked against all stocks. Put another way, each stock’s composite valuation is compared to all other stocks. These ranks are then sorted into quintiles from the cheapest 20% (a grade of A) to the most expensive 20% (a grade of F).
As always, we recommend that you conduct proper due diligence and research before investing in any security. We also suggest that investors utilize numerous grades, not just value, when it comes to deciding whether a company is a good fit for their allocation needs.
Aditxt Inc’s Value Grade
Value Grade:
| Metric | Score | ADTX | Industry Median |
| Price/Sales | 14 | 0.37 | 7.08 |
| Price/Earnings | na | na | 29.4 |
| EV/EBITDA | na | na | 1.4 |
| Shareholder Yield | 99 | (605.7%) | (14.2%) |
| Price/Book Value | 1 | 0.09 | 2.10 |
| Price/Free Cash Flow | na | na | 26.7 |
Aditxt, Inc. is a biotech company focused on discovering, developing, and deploying health innovations. It develops and commercializes technologies with a focus on monitoring and modulating the immune system. Its portfolio includes Adimune, Inc., developing a new class of therapeutics designed to retrain the immune system to address organ rejection, autoimmunity, and allergies; Adivir, Inc., focused on identifying, developing, and commercializing new ways to treat infectious diseases, and Pearsanta, Inc., offering personalized lab testing, backed by CLIA-certified and CAP-accredited monitoring center. Adimune, Inc's immune modulation product candidate, ADI-100, is based on the Apoptotic DNA Immunotherapy platform technology, utilizes a novel approach that mimics the way bodies naturally induce tolerance to own tissues. It also offers electroencephalography (EEG) brain monitoring technologies and devices, including NeuroCap and NeuroEEG for telehealth and tele-neurology applications.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Aditxt Inc has a Value Score of 68, which is considered to be undervalued.
When you look at Aditxt Inc’s price-to-sales ratio at 0.37 compared to the industry median at 7.08, this company has a lower price relative to revenue compared to its peers. This could make Aditxt Inc’s stock more attractive for value investors.
Shareholder yield is the sum of a stock’s dividend yield (paid over previous 12 months minus special dividends) and the percentage of net share buybacks over the previous 12 months. Aditxt Inc’s shareholder yield is lower than its industry median ratio of (14.20%). Value investors may look for an attractive shareholder yield because it can be a powerful tool for identifying if the company has a good management team.
As one of the most common value metrics, the price-to-book ratio evaluates a company’s current market price relative to its book value. Aditxt Inc’s price-to-book ratio is lower than its industry median ratio of 2.10. This could make Aditxt Inc more attractive to investors looking for a new addition to their portfolio.
Creative Medical Technology Holdings Inc’s Value Grade
Value Grade:
| Metric | Score | CELZ | Industry Median |
| Price/Sales | na | na | 7.08 |
| Price/Earnings | na | na | 29.4 |
| EV/EBITDA | 1 | 0.3 | 1.4 |
| Shareholder Yield | 60 | (1.4%) | (14.2%) |
| Price/Book Value | 15 | 0.67 | 2.10 |
| Price/Free Cash Flow | na | na | 26.7 |
Creative Medical Technology Holdings, Inc. is a commercial stage biotechnology company dedicated to the advancement of identifying and translating novel biological therapeutics in the fields of immunotherapy, endocrinology, urology, neurology and orthopedics. The Company conducts substantially all of its commercial operations through its subsidiary, Creative Medical Technologies, Inc. Its products include AlloStem (CELZ-201-DDT) - allogenic human perinatal tissue derived cell program (clinical phase), ImmCelz (CELZ-100) - personalized supercharged immune therapy platform (pre-clinical trials), Type I Diabetes (CELZ-201 CREATE-1) - type I diabetes, Allostemspine Chronic Lower Back Pain (CELZ 201 ADAPT), Alova, CaverStem - erectile dysfunction treatment, FemCelz - female sexual function treatment, StemSpine - regenerative stem cell procedure for the treatment of degenerative disc disease (clinical trials), and OvaStem - stem cell therapy for premature ovarian failure.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Creative Medical Technology Holdings Inc has a Value Score of 90, which is considered to be undervalued.
Creative Medical Technology Holdings Inc’s price-to-book ratio is higher than its peers. This could make Creative Medical Technology Holdings Inc less attractive for value investors when compared to the industry median at 2.10.
You can read more about Creative Medical Technology Holdings Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Genprex Inc’s Value Grade
Value Grade:
| Metric | Score | GNPX | Industry Median |
| Price/Sales | na | na | 7.08 |
| Price/Earnings | na | na | 29.4 |
| EV/EBITDA | 0 | 0.1 | 1.4 |
| Shareholder Yield | 88 | (30.8%) | (14.2%) |
| Price/Book Value | 8 | 0.41 | 2.10 |
| Price/Free Cash Flow | na | na | 26.7 |
Genprex, Inc. is a clinical-stage gene therapy company focused on developing therapies for patients with cancer and diabetes. The Company’s technologies are designed to administer disease-fighting genes to provide new therapies for large patient populations with cancer and diabetes, who have limited treatment options. Its oncology program utilizes its systemic, non-viral Oncoprex Delivery System which encapsulates the gene-expressing plasmids using lipid nanoparticles. The Company’s lead product candidate, Reqorsa Immunogene Therapy (quaratusugene ozeplasmid), is being evaluated in three clinical trials as a treatment for non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Using a different gene therapy delivery system, the Company is also developing its preclinical diabetes candidate GPX-002 using the same construct for both Type 1 diabetes and Type 2 diabetes. It conducts preclinical research to explore how REQORSA may be administered in other solid tumors.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Genprex Inc has a Value Score of 79, which is considered to be undervalued.
Genprex Inc’s price-to-book ratio is higher than its peers. This could make Genprex Inc less attractive for value investors when compared to the industry median at 2.10.
You can read more about Genprex Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Histogen Inc’s Value Grade
Value Grade:
| Metric | Score | HSTO | Industry Median |
| Price/Sales | na | na | 7.08 |
| Price/Earnings | na | na | 29.4 |
| EV/EBITDA | 0 | 0.2 | 1.4 |
| Shareholder Yield | 85 | (20.2%) | (14.2%) |
| Price/Book Value | 2 | 0.13 | 2.10 |
| Price/Free Cash Flow | na | na | 26.7 |
Histogen Inc. is a clinical-stage therapeutics company. The Company is focused on developing clinical and preclinical small molecule pan-caspase and caspase selective inhibitors that protect the body’s natural process to restore immune function. Its product candidates include emricasan, CTS-2090 and CTS-2096. It develops emricasan for acute bacterial skin and skin structure infections (ABSSSI) as well evaluating its use for other infectious diseases. Its pipeline also includes novel preclinical product candidates including CTS-2090 and CTS-2096, which are selective small molecule inhibitors of caspase-1 designed for the treatment of certain inflammatory diseases. Emricasan is an orally available pan-caspase inhibitor designed to reduce the activities of human caspases, which are enzymes that mediate inflammation and apoptosis. CTS-2090 and CTS-2096 are selective caspase-1 inhibitors targeting inflammasome activation and to treat a variety of inflammation mediated diseases.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Histogen Inc has a Value Score of 84, which is considered to be undervalued.
Histogen Inc’s price-to-book ratio is higher than its peers. This could make Histogen Inc less attractive for value investors when compared to the industry median at 2.10.
You can read more about Histogen Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Palisade Bio Inc’s Value Grade
Value Grade:
| Metric | Score | PALI | Industry Median |
| Price/Sales | na | na | 7.08 |
| Price/Earnings | na | na | 29.4 |
| EV/EBITDA | 1 | 0.5 | 1.4 |
| Shareholder Yield | 97 | (167.0%) | (14.2%) |
| Price/Book Value | 7 | 0.37 | 2.10 |
| Price/Free Cash Flow | na | na | 26.7 |
Palisade Bio, Inc. is a biopharmaceutical company focused on developing novel therapeutics for serious chronic gastrointestinal diseases. It is engaged in advancing a PALI-2108 for the treatment of IBD, including UC and CD and are researching PALI-1908. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract. UC primarily affects the colon and the rectum. CD can affect any part of the gastrointestinal tract, from the mouth to the anus. PALI-2108 is a prodrug PDE4 inhibitor that operates through a mechanism within colon tissues, targeting the key enzyme phosphodiesterase-4 (PDE4). This enzyme is pivotal in cAMP hydrolysis, and by inhibiting PDE4, intracellular cAMP levels are elevated. This elevation leads to the downregulation of inflammatory cytokines and a reduction in the expression of cell adhesion molecules. By modulating these processes, PALI-2108 prevents the local infiltration and activation of inflammatory cells in the colon tissues.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Palisade Bio Inc has a Value Score of 73, which is considered to be undervalued.
Palisade Bio Inc’s price-to-book ratio is higher than its peers. This could make Palisade Bio Inc less attractive for value investors when compared to the industry median at 2.10.
You can read more about Palisade Bio Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Tenax Therapeutics Inc’s Value Grade
Value Grade:
| Metric | Score | TENX | Industry Median |
| Price/Sales | na | na | 7.08 |
| Price/Earnings | na | na | 29.4 |
| EV/EBITDA | 2 | 0.7 | 1.4 |
| Shareholder Yield | 100 | (948.2%) | (14.2%) |
| Price/Book Value | 6 | 0.34 | 2.10 |
| Price/Free Cash Flow | na | na | 26.7 |
Tenax Therapeutics, Inc. is a Phase 3 development-stage pharmaceutical company. The Company is focused on identifying, developing, and commercializing products that address cardiovascular and pulmonary diseases with high unmet medical needs. The Company's products include TNX-201 (oral enteric coated imatinib) and TNX-103 (oral levosimendan). The Company is developing dosing and a formulation of imatinib mesylate, a kinase inhibitor for the treatment of pulmonary arterial hypertension (PAH). The Company’s other programs include TNX-101 (IV), TNX-102 (subcutaneous) and TNX-103 (oral) levosimendan. Levosimendan is a calcium sensitizer/K-ATP activator developed for intravenous use in hospitalized patients with acutely decompensated heart failure. The Company has completed the Phase II trial of levosimendan in patients with PH and heart failure with preserved ejection fraction (HFpEF).
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Tenax Therapeutics Inc has a Value Score of 71, which is considered to be undervalued.
Tenax Therapeutics Inc’s price-to-book ratio is higher than its peers. This could make Tenax Therapeutics Inc less attractive for value investors when compared to the industry median at 2.10.
You can read more about Tenax Therapeutics Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Exicure Inc’s Value Grade
Value Grade:
| Metric | Score | XCUR | Industry Median |
| Price/Sales | 5 | 0.13 | 7.08 |
| Price/Earnings | 0 | 0.2 | 29.4 |
| EV/EBITDA | 2 | 0.8 | 1.4 |
| Shareholder Yield | 94 | (74.3%) | (14.2%) |
| Price/Book Value | 14 | 0.63 | 2.10 |
| Price/Free Cash Flow | na | na | 26.7 |
Exicure, Inc. is an early-stage biotechnology company focused on developing nucleic acid therapies targeting ribonucleic acid against validated targets. The Company is developing nucleic acid therapies targeting ribonucleic acid (RNA) to address both genetic and non-genetic neurological disorders. Its lead program is a non-opioid pain analgesic directed against the genetically validated target SCN9A. It is engaged in discovery efforts across a range of indications and therapeutic targets, such as pain using non-opioid analgesics, as well as rare neurological genetic disorders, including Huntington's disease, Angelman Syndrome, Batten disease, spinocerebellar ataxia, and sporadic amyotrophic lateral sclerosis (ALS). The Company focuses on pursuing out-licensing opportunities for its clinical asset, cavrotolimod, as well as for its preclinical candidates, including the SCN9A program for neuropathic pain.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Exicure Inc has a Value Score of 92, which is considered to be undervalued.
Exicure Inc’s price-earnings ratio is 0.2 compared to the industry median at 29.4. This means that it has a lower price relative to its earnings compared to its peers. This makes Exicure Inc more attractive for value investors.
Exicure Inc’s price-to-book ratio is higher than its peers. This could make Exicure Inc less attractive for value investors when compared to the industry median at 2.10.
You can read more about Exicure Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Other Biotechnology & Medical Research Stock Grades
Value is just one of the five Stock Grades included in our A+ Investor service. AAII members can see the top-graded stocks—those with grades of A or B for value, growth, momentum, earnings estimate revisions and quality—on the A+ Stock Grades Screener.
Also, if you want full access to all of AAII’s premium services, you can subscribe to one convenient bundled plan called AAII Platinum where you can try out A+ Investor, AAII Dividend Investing, the Stock Superstars Report, Growth Investing and VMQ Stocks. With the other premium services, you can dive deep into additional metrics, portfolios, commentary and information about Biotechnology & Medical Research stocks as well as other industrys.
Choosing Which of the 7 Best Biotechnology & Medical Research Stocks Is Right for You
Choosing which value stocks to invest in will ultimately depend on your individual goals and allocation; however, comparing similar value stocks in the same industry can help you analyze which might be better investments for you in the long run. So, let’s take a look at the Value Grade for all of our stocks.
- Aditxt Inc stock has a Value Grade of B.
- Creative Medical Technology Holdings Inc stock has a Value Grade of A.
- Genprex Inc stock has a Value Grade of B.
- Histogen Inc stock has a Value Grade of A.
- Palisade Bio Inc stock has a Value Grade of B.
- Tenax Therapeutics Inc stock has a Value Grade of B.
- Exicure Inc stock has a Value Grade of A.
Now that you have a bit more background about each of the 7 undervalued stocks in the Biotechnology & Medical Research industry as well as their overall grades, it’s time for you to conduct additional research to see if these could fit your portfolio needs based on your goals and risk tolerance. AAII can help you figure out both and identify which investments align with what works best for you.
We do so through a program of education that teaches you to invest for yourself and become an effective manager of your own wealth—no more relying on others for your financial independence. You can rely on AAII for timeless articles on financial planning and stock-picking, unbiased research and actionable analysis that makes you a better investor.
A+ Investor adds to that qualitative teaching by giving you a powerful data suite that helps you whittle down investment decisions to find stocks, exchange-traded funds (ETFs) or mutual funds that meet your needs.
Additional Resources About Biotechnology & Medical Research Stocks
Want to learn more about Biotechnology & Medical Research stocks to see if they could be the right investment for you? Check out some additional resources and articles to help you on your financial journey.
- 7 Undervalued Biotechnology & Medical Research Stocks for Tuesday, May 28
- 4 Undervalued Biotechnology & Medical Research Stocks for Monday, May 27
- 7 Undervalued Biotechnology & Medical Research Stocks for Friday, May 24
- Why Adlai Nortye Ltd (ADR)’s (ANL) Stock Is Down 12.72%
AAII Disclaimer
We make no representations or warranties that any investor will, or is likely to, achieve profits similar to those shown, because past, hypothetical or simulated performance is not necessarily indicative of future results. Before making an investment decision, you should consider your circumstances and whether the information on our content is applicable to your situation. This information was prepared in good faith and we accept no liability for any errors or omissions. The full disclaimer can be read here.
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