Based on key financial metrics such as the price-to-sales ratio, shareholder yield and the price-earnings ratio, the following 7 stocks made the list for top value stocks in the Biotechnology & Medical Research industry. Those looking for value stocks to add to their portfolio may want to use this list as a starting point for further investment research.
Why Focus on Undervalued Biotechnology & Medical Research Stocks?
Value investors seek to buy stocks at a discount to their intrinsic value. Long-term returns show that such strategies are advantageous. Value stocks, as a group, tend to outperform growth stocks over extended periods of time. Typically, value investors perform financial analysis of numerous metrics, don’t follow the herd and are long-term investors.
AAII’s A+ Investor Value Grade is derived from a stock’s Value Score. The Value Score is the percentile rank of the average of the percentile ranks of the price-to-sales ratio, price-earnings ratio, enterprise-value-to-EBITDA (EV/EBITDA) ratio, shareholder yield, price-to-book-value ratio and price-to-free-cash-flow ratio. The score is variable, meaning it can consider all six ratios or, should any of the six ratios not be valid, the remaining ratios that are valid. To be assigned a Value Score, stocks must have a valid (non-null) ratio and corresponding ranking for at least two of the six valuation ratios.
What Goes Into AAII’s Value Grade?
Stock evaluation requires access to huge amounts of data as well as the knowledge and time to sift through it all, make sense of financial ratios, read income statements and analyze recent stock movement. AAII created A+ Investor, a robust data suite that condenses data research in an actionable and customizable way suitable for investors of all knowledge levels, to help investors with that task.
AAII’s proprietary stock grades come with A+ Investor. These offer intuitive A–F grades for more than just value. It is possible for a stock to appear cheap based on one valuation metric but appear expensive on another. It is also possible for one valuation ratio to be associated with outperforming stocks during certain periods of time but not others. Some stocks may even have null values for certain metrics like the price-earnings ratio or the price-to-book ratio but not others. An example of this would be a company with losses instead of profits or a negative book value because of heavy borrowing. Negative earnings or book value result in non-meaningful ratios that are left blank or null.
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7 Undervalued Biotechnology & Medical Research Stocks
Of course, there are countless value stocks that are worth mentioning, but this is a concise list of the top 7 undervalued stocks in the Biotechnology & Medical Research industry for Friday, June 21, 2024. Let’s take a closer look at their individual scores to see how they measure up against each other and the Biotechnology & Medical Research industry median.
| Company | Ticker | Price/Sales | Price/Earnings | EV/EBITDA | Shareholder Yield | Price/Book Value | Price/Free Cash Flow | Value Grade |
| Estrella Immunopharma Inc | ESLA | na | na | 4.7 | 82.0% | 0.09 | na | A |
| Genprex Inc | GNPX | na | na | 0.1 | (30.8%) | 0.38 | na | B |
| Histogen Inc | HSTO | na | na | 0.2 | (20.2%) | 0.15 | na | A |
| InMed Pharmaceuticals Inc | INM | 0.41 | na | 0.6 | (188.8%) | 0.21 | na | A |
| Personalis Inc | PSNL | 0.84 | na | na | (8.4%) | 0.52 | na | B |
| Salarius Pharmaceuticals Inc | SLRX | na | na | 0.2 | (75.4%) | 0.40 | na | B |
| SQZ Biotechnologies Co | SQZB | 0.09 | na | 0.1 | (0.7%) | 0.58 | na | A |
The Value Grade is assigned based on how each stock’s composite valuation compares to all other stocks.
The process for assigning grades starts with each variable for a given stock. The percentile rankings for all valid ratios that a stock has are calculated. So, for instance, a stock could have a price-to-book ranking in the 43rd percentile, a price-earnings ranking in the 67th percentile, a price-to-sales ranking in the 23rd percentile, etc. Then, those rankings are averaged for each stock. (A minimum of two valid variables are required, though all six will be used if available.)
Once the average of the individual variables is calculated, that average is ranked against all stocks. Put another way, each stock’s composite valuation is compared to all other stocks. These ranks are then sorted into quintiles from the cheapest 20% (a grade of A) to the most expensive 20% (a grade of F).
As always, we recommend that you conduct proper due diligence and research before investing in any security. We also suggest that investors utilize numerous grades, not just value, when it comes to deciding whether a company is a good fit for their allocation needs.
Estrella Immunopharma Inc’s Value Grade
Value Grade:
| Metric | Score | ESLA | Industry Median |
| Price/Sales | na | na | 6.64 |
| Price/Earnings | na | na | 28.5 |
| EV/EBITDA | 13 | 4.7 | 1.6 |
| Shareholder Yield | 0 | 82.0% | (15.1%) |
| Price/Book Value | 1 | 0.09 | 1.82 |
| Price/Free Cash Flow | na | na | 25.2 |
Estrella Immunopharma, Inc. is a preclinical-stage biopharmaceutical company. The Company is developing CD19 and CD22-targeted ARTEMIS T-cell therapies with the capacity to address treatment challenges for patients with blood cancers and solid tumors. Its lead product candidate, EB103, utilizes Eureka's ARTEMIS technology to target CD19, a protein expressed on the surface of almost all B-cell leukemias and lymphomas. The Company is also developing EB104, which also utilizes Eureka's ARTEMIS technology to target not only CD19, but also CD22, a protein that, like CD19, is expressed on the surface of most B-cell malignancies. The Company is also collaborating with Imugene Limited and its product candidate, CF33-CD19t an oncolytic virus (CF33-CD19t), to research the use of EB103 in conjunction with CF33-CD19t to treat solid tumors.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Estrella Immunopharma Inc has a Value Score of 100, which is considered to be undervalued.
Now, let’s assess Estrella Immunopharma Inc’s EV/EBITDA ratio, also known as enterprise multiple. At 4.7, when compared to the industry median of 1.6, the company may be considered overvalued in relation to its peers. Value investors could use the enterprise multiple to identify stocks that are considered overvalued or undervalued relative to their industry.
Shareholder yield is the sum of a stock’s dividend yield (paid over previous 12 months minus special dividends) and the percentage of net share buybacks over the previous 12 months. Estrella Immunopharma Inc’s shareholder yield is higher than its industry median ratio of (15.09%). Value investors may look for an attractive shareholder yield because it can be a powerful tool for identifying if the company has a good management team.
As one of the most common value metrics, the price-to-book ratio evaluates a company’s current market price relative to its book value. Estrella Immunopharma Inc’s price-to-book ratio is lower than its industry median ratio of 1.82. This could make Estrella Immunopharma Inc more attractive to investors looking for a new addition to their portfolio.
Genprex Inc’s Value Grade
Value Grade:
| Metric | Score | GNPX | Industry Median |
| Price/Sales | na | na | 6.64 |
| Price/Earnings | na | na | 28.5 |
| EV/EBITDA | 0 | 0.1 | 1.6 |
| Shareholder Yield | 88 | (30.8%) | (15.1%) |
| Price/Book Value | 7 | 0.38 | 1.82 |
| Price/Free Cash Flow | na | na | 25.2 |
Genprex, Inc. is a clinical-stage gene therapy company focused on developing therapies for patients with cancer and diabetes. The Company’s technologies are designed to administer disease-fighting genes to provide new therapies for large patient populations with cancer and diabetes, who have limited treatment options. Its oncology program utilizes its systemic, non-viral Oncoprex Delivery System which encapsulates the gene-expressing plasmids using lipid nanoparticles. The Company’s lead product candidate, Reqorsa Immunogene Therapy (quaratusugene ozeplasmid), is being evaluated in three clinical trials as a treatment for non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Using a different gene therapy delivery system, the Company is also developing its preclinical diabetes candidate GPX-002 using the same construct for both Type 1 diabetes and Type 2 diabetes. It conducts preclinical research to explore how REQORSA may be administered in other solid tumors.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Genprex Inc has a Value Score of 80, which is considered to be undervalued.
Genprex Inc’s price-to-book ratio is higher than its peers. This could make Genprex Inc less attractive for value investors when compared to the industry median at 1.82.
You can read more about Genprex Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Histogen Inc’s Value Grade
Value Grade:
| Metric | Score | HSTO | Industry Median |
| Price/Sales | na | na | 6.64 |
| Price/Earnings | na | na | 28.5 |
| EV/EBITDA | 1 | 0.2 | 1.6 |
| Shareholder Yield | 84 | (20.2%) | (15.1%) |
| Price/Book Value | 2 | 0.15 | 1.82 |
| Price/Free Cash Flow | na | na | 25.2 |
Histogen Inc. is a clinical-stage therapeutics company. The Company is focused on developing clinical and preclinical small molecule pan-caspase and caspase selective inhibitors that protect the body’s natural process to restore immune function. Its product candidates include emricasan, CTS-2090 and CTS-2096. It develops emricasan for acute bacterial skin and skin structure infections (ABSSSI) as well evaluating its use for other infectious diseases. Its pipeline also includes novel preclinical product candidates including CTS-2090 and CTS-2096, which are selective small molecule inhibitors of caspase-1 designed for the treatment of certain inflammatory diseases. Emricasan is an orally available pan-caspase inhibitor designed to reduce the activities of human caspases, which are enzymes that mediate inflammation and apoptosis. CTS-2090 and CTS-2096 are selective caspase-1 inhibitors targeting inflammasome activation and to treat a variety of inflammation mediated diseases.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Histogen Inc has a Value Score of 85, which is considered to be undervalued.
Histogen Inc’s price-to-book ratio is higher than its peers. This could make Histogen Inc less attractive for value investors when compared to the industry median at 1.82.
You can read more about Histogen Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
InMed Pharmaceuticals Inc’s Value Grade
Value Grade:
| Metric | Score | INM | Industry Median |
| Price/Sales | 16 | 0.41 | 6.64 |
| Price/Earnings | na | na | 28.5 |
| EV/EBITDA | 2 | 0.6 | 1.6 |
| Shareholder Yield | 97 | (188.8%) | (15.1%) |
| Price/Book Value | 3 | 0.21 | 1.82 |
| Price/Free Cash Flow | na | na | 25.2 |
InMed Pharmaceuticals Inc. is a clinical-stage pharmaceutical company. The Company is engaged in developing a pipeline of prescription-based products, including rare cannabinoids and cannabinoid analogs, targeting the treatment of diseases with high unmet medical needs, as well as developing proprietary manufacturing technologies to produce rare cannabinoids for sale in the health and wellness industry. Its segments include InMed Pharmaceuticals and BayMedica. The InMed Pharmaceuticals segment is engaged in research and development of cannabinoid-based pharmaceutical products. The BayMedica segment is focused on developing manufacturing technologies to produce rare cannabinoids for sale in the health and wellness industry. Its two product candidates include INM-755 and INM-088. INM-755 is developed as a topical skin cream formulation containing cannabinol (CBN) for the treatment of symptoms related to Epidermolysis Bullosa (EB). INM-088 is used for the treatment of glaucoma.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
InMed Pharmaceuticals Inc has a Value Score of 84, which is considered to be undervalued.
InMed Pharmaceuticals Inc’s price-to-book ratio is higher than its peers. This could make InMed Pharmaceuticals Inc less attractive for value investors when compared to the industry median at 1.82.
You can read more about InMed Pharmaceuticals Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Personalis Inc’s Value Grade
Value Grade:
| Metric | Score | PSNL | Industry Median |
| Price/Sales | 30 | 0.84 | 6.64 |
| Price/Earnings | na | na | 28.5 |
| EV/EBITDA | na | na | 1.6 |
| Shareholder Yield | 77 | (8.4%) | (15.1%) |
| Price/Book Value | 11 | 0.52 | 1.82 |
| Price/Free Cash Flow | na | na | 25.2 |
Personalis, Inc. is engaged in developing and marketing advanced cancer genomic tests and analytics. The Company’s advanced genomic sequencing and analytics support the development of personalized cancer vaccines and other next generation cancer immunotherapies. Its products include NeXT Personal, ImmunoI DNeXT, NeXT Personal Dx, NeXT Dx, whole exome sequencing (WES), and whole genome sequencing (WGS). NeXT Personal is a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD) and recurrence in cancer. NeXT Dx is a comprehensive tumor profiling test that unlocks the entire exome (DNA) and transcriptome (RNA) with matched tumor-normal analysis. The Company performed WGS on human samples for research projects, such as population sequencing initiatives. The Company’s tests and analytics are used by pharmaceutical companies for translational research, biomarker discovery, the development of personalized cancer therapies.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Personalis Inc has a Value Score of 66, which is considered to be undervalued.
Personalis Inc’s price-to-book ratio is higher than its peers. This could make Personalis Inc less attractive for value investors when compared to the industry median at 1.82.
You can read more about Personalis Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Salarius Pharmaceuticals Inc’s Value Grade
Value Grade:
| Metric | Score | SLRX | Industry Median |
| Price/Sales | na | na | 6.64 |
| Price/Earnings | na | na | 28.5 |
| EV/EBITDA | 1 | 0.2 | 1.6 |
| Shareholder Yield | 94 | (75.4%) | (15.1%) |
| Price/Book Value | 8 | 0.40 | 1.82 |
| Price/Free Cash Flow | na | na | 25.2 |
Salarius Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is developing treatments for parties with cancers in need of new treatment options. Its product portfolio includes seclidemstat, an oral novel small molecule inhibitor of the LSD1 enzyme and the Company's lead candidate, which is being studied as a potential treatment for pediatric cancers, sarcomas, and other cancers with limited treatment options, and SP-3164, an oral small molecule protein degrader being developed for the treatment of Non-Hodgkins Lymphoma. SP-3164 is a small molecule protein degrader, and seclidemstat (SP-2577) is a small molecule inhibitor. SP-3164 is a next-generation cereblon-binding molecular glue (MG). SP-2577 is a small-molecule LSD1 inhibitor with a novel scaffold. The molecule was discovered using structure-based computational screening coupled with chemical screening and further optimization with structure-activity relationship studies.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Salarius Pharmaceuticals Inc has a Value Score of 75, which is considered to be undervalued.
Salarius Pharmaceuticals Inc’s price-to-book ratio is higher than its peers. This could make Salarius Pharmaceuticals Inc less attractive for value investors when compared to the industry median at 1.82.
You can read more about Salarius Pharmaceuticals Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
SQZ Biotechnologies Co’s Value Grade
Value Grade:
| Metric | Score | SQZB | Industry Median |
| Price/Sales | 4 | 0.09 | 6.64 |
| Price/Earnings | na | na | 28.5 |
| EV/EBITDA | 0 | 0.1 | 1.6 |
| Shareholder Yield | 55 | (0.7%) | (15.1%) |
| Price/Book Value | 13 | 0.58 | 1.82 |
| Price/Free Cash Flow | na | na | 25.2 |
SQZ Biotechnologies Company is a clinical-stage biotechnology company. The Company is focused on unlocking the full potential of cell therapies to benefit patients. In oncology, it is developing cell therapy platforms that are based on directing tumor antigen-specific immune activation via engineered antigen presentation. Its clinical-stage cell therapy candidates include SQZ Enhanced APC (eAPC) Platform, SQZ Activating Antigen Carrier (AAC) Platform and SQZ Tolerizing Antigen Carrier (TAC) Platform. The SQZ eAPC platform is the second-generation product candidate designed to generate tumor specific CD8+ T cell activation to drive the antitumor immune response. The SQZ AAC platform is designed to induce antigen presentation in vivo by deriving antigen carriers from engineering red blood cells (RBCs) with tumor specific antigens and adjuvants. Its SQZ TAC platform is designed to induce antigen-specific immune tolerance in vivo by utilizing a similar approach to the AAC platform.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
SQZ Biotechnologies Co has a Value Score of 97, which is considered to be undervalued.
SQZ Biotechnologies Co’s price-to-book ratio is higher than its peers. This could make SQZ Biotechnologies Co less attractive for value investors when compared to the industry median at 1.82.
You can read more about SQZ Biotechnologies Co’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Other Biotechnology & Medical Research Stock Grades
Value is just one of the five Stock Grades included in our A+ Investor service. AAII members can see the top-graded stocks—those with grades of A or B for value, growth, momentum, earnings estimate revisions and quality—on the A+ Stock Grades Screener.
Also, if you want full access to all of AAII’s premium services, you can subscribe to one convenient bundled plan called AAII Platinum where you can try out A+ Investor, AAII Dividend Investing, the Stock Superstars Report, Growth Investing and VMQ Stocks. With the other premium services, you can dive deep into additional metrics, portfolios, commentary and information about Biotechnology & Medical Research stocks as well as other industrys.
Choosing Which of the 7 Best Biotechnology & Medical Research Stocks Is Right for You
Choosing which value stocks to invest in will ultimately depend on your individual goals and allocation; however, comparing similar value stocks in the same industry can help you analyze which might be better investments for you in the long run. So, let’s take a look at the Value Grade for all of our stocks.
- Estrella Immunopharma Inc stock has a Value Grade of A.
- Genprex Inc stock has a Value Grade of B.
- Histogen Inc stock has a Value Grade of A.
- InMed Pharmaceuticals Inc stock has a Value Grade of A.
- Personalis Inc stock has a Value Grade of B.
- Salarius Pharmaceuticals Inc stock has a Value Grade of B.
- SQZ Biotechnologies Co stock has a Value Grade of A.
Now that you have a bit more background about each of the 7 undervalued stocks in the Biotechnology & Medical Research industry as well as their overall grades, it’s time for you to conduct additional research to see if these could fit your portfolio needs based on your goals and risk tolerance. AAII can help you figure out both and identify which investments align with what works best for you.
We do so through a program of education that teaches you to invest for yourself and become an effective manager of your own wealth—no more relying on others for your financial independence. You can rely on AAII for timeless articles on financial planning and stock-picking, unbiased research and actionable analysis that makes you a better investor.
A+ Investor adds to that qualitative teaching by giving you a powerful data suite that helps you whittle down investment decisions to find stocks, exchange-traded funds (ETFs) or mutual funds that meet your needs.
Additional Resources About Biotechnology & Medical Research Stocks
Want to learn more about Biotechnology & Medical Research stocks to see if they could be the right investment for you? Check out some additional resources and articles to help you on your financial journey.
- 7 Undervalued Biotechnology & Medical Research Stocks for Friday, June 21
- 5 Undervalued Biotechnology & Medical Research Stocks for Thursday, June 20
- Why CG Oncology Inc’s (CGON) Stock Is Down 5.25%
- Why Exact Sciences Corp’s (EXAS) Stock Is Up 4.96%
AAII Disclaimer
We make no representations or warranties that any investor will, or is likely to, achieve profits similar to those shown, because past, hypothetical or simulated performance is not necessarily indicative of future results. Before making an investment decision, you should consider your circumstances and whether the information on our content is applicable to your situation. This information was prepared in good faith and we accept no liability for any errors or omissions. The full disclaimer can be read here.
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