7 Undervalued Biotechnology Stocks for Thursday, October 31

By Tudor Pop
October 31, 2024
Diamond graphic indicating best value stocks in their industry
Featured Tickers:

Based on key financial metrics such as the price-to-sales ratio, shareholder yield and the price-earnings ratio, the following 7 stocks made the list for top value stocks in the Biotechnology industry. Those looking for value stocks to add to their portfolio may want to use this list as a starting point for further investment research.

Why Focus on Undervalued Biotechnology Stocks?

Value investors seek to buy stocks at a discount to their intrinsic value. Long-term returns show that such strategies are advantageous. Value stocks, as a group, tend to outperform growth stocks over extended periods of time. Typically, value investors perform financial analysis of numerous metrics, don’t follow the herd and are long-term investors.

AAII’s A+ Investor Value Grade is derived from a stock’s Value Score. The Value Score is the percentile rank of the average of the percentile ranks of the price-to-sales ratio, price-earnings ratio, enterprise-value-to-EBITDA (EV/EBITDA) ratio, shareholder yield, price-to-book-value ratio and price-to-free-cash-flow ratio. The score is variable, meaning it can consider all six ratios or, should any of the six ratios not be valid, the remaining ratios that are valid. To be assigned a Value Score, stocks must have a valid (non-null) ratio and corresponding ranking for at least two of the six valuation ratios.

What Goes Into AAII’s Value Grade?

Stock evaluation requires access to huge amounts of data as well as the knowledge and time to sift through it all, make sense of financial ratios, read income statements and analyze recent stock movement. AAII created A+ Investor, a robust data suite that condenses data research in an actionable and customizable way suitable for investors of all knowledge levels, to help investors with that task.

AAII’s proprietary stock grades come with A+ Investor. These offer intuitive A–F grades for more than just value. It is possible for a stock to appear cheap based on one valuation metric but appear expensive on another. It is also possible for one valuation ratio to be associated with outperforming stocks during certain periods of time but not others. Some stocks may even have null values for certain metrics like the price-earnings ratio or the price-to-book ratio but not others. An example of this would be a company with losses instead of profits or a negative book value because of heavy borrowing. Negative earnings or book value result in non-meaningful ratios that are left blank or null.

Click the button below to learn more about A+ Investor and subscribe today.

Learn More About A+ Investor

7 Undervalued Biotechnology Stocks

Of course, there are countless value stocks that are worth mentioning, but this is a concise list of the top 7 undervalued stocks in the Biotechnology industry for Thursday, October 31, 2024. Let’s take a closer look at their individual scores to see how they measure up against each other and the Biotechnology industry median.

Company Ticker Price/Sales Price/Earnings EV/EBITDA Shareholder Yield Price/Book Value Price/Free Cash Flow Value Grade
Aadi Bioscience, Inc. AADI 2.22 na na (0.5%) 0.50 na B
Azitra, Inc. AZTR 0.66 na na 0.0% 0.17 na A
HOOKIPA Pharma Inc. HOOK 0.77 na 0.7 (51.6%) 0.54 na B
Lisata Therapeutics, Inc. LSTA na na 0.9 (3.6%) 0.49 na A
Silo Pharma, Inc. SILO na na 0.8 3.2% 0.57 na A
Salarius Pharmaceuticals, Inc. SLRX na na 0.5 (77.3%) 0.18 na B
XBiotech Inc. XBIT na na 0.1 (0.1%) 1.03 na A

The Value Grade is assigned based on how each stock’s composite valuation compares to all other stocks.

The process for assigning grades starts with each variable for a given stock. The percentile rankings for all valid ratios that a stock has are calculated. So, for instance, a stock could have a price-to-book ranking in the 43rd percentile, a price-earnings ranking in the 67th percentile, a price-to-sales ranking in the 23rd percentile, etc. Then, those rankings are averaged for each stock. (A minimum of two valid variables are required, though all six will be used if available.)

Once the average of the individual variables is calculated, that average is ranked against all stocks. Put another way, each stock’s composite valuation is compared to all other stocks. These ranks are then sorted into quintiles from the cheapest 20% (a grade of A) to the most expensive 20% (a grade of F).

As always, we recommend that you conduct proper due diligence and research before investing in any security. We also suggest that investors utilize numerous grades, not just value, when it comes to deciding whether a company is a good fit for their allocation needs.

Aadi Bioscience, Inc.’s Value Grade

Value Grade:

Metric Score AADI Industry Median
Price/Sales 55 2.22 7.94
Price/Earnings na na 24.4
EV/EBITDA na na 0.8
Shareholder Yield 55 (0.5%) (16.6%)
Price/Book Value 14 0.50 2.04
Price/Free Cash Flow na na 28.3

Aadi Bioscience, Inc., a biopharmaceutical company, engages in developing and commercializing precision therapies for genetically defined cancers with alterations in mTOR pathway genes. Its lead drug product candidate comprises FYARRO, a form of sirolimus protein-bound particles for injectable suspension for the treatment in adult patients with advanced unresectable or metastatic malignant PEComa. The company is also involved in evaluating FYARRO in cancers, including indications targeting specific genomic alterations that activate the mTOR pathway. Aadi Bioscience, Inc. was incorporated in 2007 and is headquartered in Pacific Palisades, California.

Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.

Aadi Bioscience, Inc. has a Value Score of 61, which is considered to be undervalued.

When you look at Aadi Bioscience, Inc.’s price-to-sales ratio at 2.22 compared to the industry median at 7.94, this company has a lower price relative to revenue compared to its peers. This could make Aadi Bioscience, Inc.’s stock more attractive for value investors.

Shareholder yield is the sum of a stock’s dividend yield (paid over previous 12 months minus special dividends) and the percentage of net share buybacks over the previous 12 months. Aadi Bioscience, Inc.’s shareholder yield is higher than its industry median ratio of (16.55%). Value investors may look for an attractive shareholder yield because it can be a powerful tool for identifying if the company has a good management team.

As one of the most common value metrics, the price-to-book ratio evaluates a company’s current market price relative to its book value. Aadi Bioscience, Inc.’s price-to-book ratio is lower than its industry median ratio of 2.04. This could make Aadi Bioscience, Inc. more attractive to investors looking for a new addition to their portfolio.

Azitra, Inc.’s Value Grade

Value Grade:

Metric Score AZTR Industry Median
Price/Sales 24 0.66 7.94
Price/Earnings na na 24.4
EV/EBITDA na na 0.8
Shareholder Yield 49 0.0% (16.6%)
Price/Book Value 5 0.17 2.04
Price/Free Cash Flow na na 28.3

Azitra, Inc., an early-stage biopharmaceutical company, develops therapies for precision dermatology using engineered proteins and live biotherapeutic products to treat skin diseases. It develops ATR-12, a genetically modified strain of S. epidermidis, which is in Phase Ib clinical trial for treating Netherton syndrome, a skin disease. The company also develops ATR-04, a genetically modified strain of S. epidermidis for treating the papulopustular rash experienced by cancer patients undergoing epidermal growth factor receptor inhibitor; and ATR-01, an engineered recombinant human filaggrin protein for treating ichthyosis vulgaris, a skin disease. It has a collaboration with Bayer. The company was incorporated in 2014 and is based in Branford, Connecticut.

Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.

Azitra, Inc. has a Value Score of 89, which is considered to be undervalued.

Azitra, Inc.’s price-to-book ratio is higher than its peers. This could make Azitra, Inc. less attractive for value investors when compared to the industry median at 2.04.

You can read more about Azitra, Inc.’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.

HOOKIPA Pharma Inc.’s Value Grade

Value Grade:

Metric Score HOOK Industry Median
Price/Sales 27 0.77 7.94
Price/Earnings na na 24.4
EV/EBITDA 2 0.7 0.8
Shareholder Yield 92 (51.6%) (16.6%)
Price/Book Value 15 0.54 2.04
Price/Free Cash Flow na na 28.3

HOOKIPA Pharma Inc., a clinical stage biopharmaceutical company, develops immunotherapeutics targeting infectious diseases and cancers based on its proprietary arenavirus platform. The company’s lead infectious disease product candidate is HB-200 for the treatment of pembrolizumab which is in Phase 2 of clinical trial; HB-700, a preclinical development for treatment of KRAS mutated cancers, including lung, colorectal, and pancreatic cancers. Its lead product candidates are HB-400 for the treatment of Hepatitis B which is in Phase I of clinical trial and HB-500 for the treatment of HIV which is in Phase I of clinical trial. The company’s preclinical stage products include HB-300 program for prostate cancer. It has a collaboration with Gilead Sciences, Inc. to collaborate on preclinical research programs to evaluate potential vaccine products using or incorporating its replicating and non-replicating technology platforms for the treatment, cure, diagnosis, or prevention of Hepatitis B Virus. HOOKIPA Pharma Inc. was incorporated in 2011 and is headquartered in New York, New York.

Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.

HOOKIPA Pharma Inc. has a Value Score of 76, which is considered to be undervalued.

HOOKIPA Pharma Inc.’s price-to-book ratio is higher than its peers. This could make HOOKIPA Pharma Inc. less attractive for value investors when compared to the industry median at 2.04.

You can read more about HOOKIPA Pharma Inc.’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.

Lisata Therapeutics, Inc.’s Value Grade

Value Grade:

Metric Score LSTA Industry Median
Price/Sales na na 7.94
Price/Earnings na na 24.4
EV/EBITDA 3 0.9 0.8
Shareholder Yield 71 (3.6%) (16.6%)
Price/Book Value 13 0.49 2.04
Price/Free Cash Flow na na 28.3

Lisata Therapeutics, Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of innovative therapies for the treatment of solid tumors and other diseases. Its product candidates include LSTA1, which is in Phase 2a and 2b clinical studies for the treatment of solid tumor, including metastatic pancreatic ductal adenocarcinoma (mPDAC), in combination with a range of anti-cancer regimens; XOWNA that is in Phase IIa clinical trial for the treatment of coronary microvascular dysfunction; and CD34+ cell therapy for the treatment of chronic kidney disease. Lisata Therapeutics, Inc. was incorporated in 1980 and is headquartered in Basking Ridge, New Jersey.

Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.

Lisata Therapeutics, Inc. has a Value Score of 85, which is considered to be undervalued.

Lisata Therapeutics, Inc.’s price-to-book ratio is higher than its peers. This could make Lisata Therapeutics, Inc. less attractive for value investors when compared to the industry median at 2.04.

You can read more about Lisata Therapeutics, Inc.’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.

Silo Pharma, Inc.’s Value Grade

Value Grade:

Metric Score SILO Industry Median
Price/Sales na na 7.94
Price/Earnings na na 24.4
EV/EBITDA 3 0.8 0.8
Shareholder Yield 24 3.2% (16.6%)
Price/Book Value 16 0.57 2.04
Price/Free Cash Flow na na 28.3

Silo Pharma Inc. operates as a developmental stage biopharmaceutical company. The company is developing therapeutics that address underserved conditions, including stress-induced psychiatric disorders, chronic pain conditions, and central nervous system (CNS) diseases. It focuses on developing traditional therapies and psychedelic treatments in formulations and drug delivery systems. The company’s lead program, SPC-15, is an intranasal treatment targeting PTSD and stress-induced anxiety disorders. It is also developing SP-26, a time-release ketamine-loaded implant for fibromyalgia and chronic pain relief. In addition, the company’s two preclinical programs comprise SPC-14, an intranasal compound for the treatment of Alzheimer’s disease, and SPU-16, a CNS-homing peptide targeting multiple sclerosis (MS). The company’s research and development programs are conducted through collaborations with Columbia University and the University of Maryland, Baltimore. The company was formerly known as Uppercut Brands, Inc. and changed its name to Silo Pharma, Inc. in September 2020. Silo Pharma, Inc. was incorporated in 2010 and is based in Sarasota, Florida.

Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.

Silo Pharma, Inc. has a Value Score of 98, which is considered to be undervalued.

Silo Pharma, Inc.’s price-to-book ratio is higher than its peers. This could make Silo Pharma, Inc. less attractive for value investors when compared to the industry median at 2.04.

You can read more about Silo Pharma, Inc.’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.

Salarius Pharmaceuticals, Inc.’s Value Grade

Value Grade:

Metric Score SLRX Industry Median
Price/Sales na na 7.94
Price/Earnings na na 24.4
EV/EBITDA 2 0.5 0.8
Shareholder Yield 94 (77.3%) (16.6%)
Price/Book Value 5 0.18 2.04
Price/Free Cash Flow na na 28.3

Salarius Pharmaceuticals, Inc., a clinical-stage biotechnology company, focuses on developing treatments for cancers with unmet medical need. Its lead candidate is Seclidemstat (SP-2577), a small molecular inhibitor which is in Phase I/II clinical trial for the treatment of advanced solid tumors, as well as Ewing sarcoma. The company also offers SP-3164, a small molecular protein degrader for the treatment of hematological and solid tumors. It has a strategic partnership with The University of Utah Research Foundation for the exclusive license with respect to patent rights protecting SP-2577 and related compounds and Cancer Prevention and Research Institute of Texas for product development activities. The company is headquartered in Houston, Texas.

Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.

Salarius Pharmaceuticals, Inc. has a Value Score of 77, which is considered to be undervalued.

Salarius Pharmaceuticals, Inc.’s price-to-book ratio is higher than its peers. This could make Salarius Pharmaceuticals, Inc. less attractive for value investors when compared to the industry median at 2.04.

You can read more about Salarius Pharmaceuticals, Inc.’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.

XBiotech Inc.’s Value Grade

Value Grade:

Metric Score XBIT Industry Median
Price/Sales na na 7.94
Price/Earnings na na 24.4
EV/EBITDA 0 0.1 0.8
Shareholder Yield 50 (0.1%) (16.6%)
Price/Book Value 33 1.03 2.04
Price/Free Cash Flow na na 28.3

XBiotech Inc., a biopharmaceutical company, discovers, develops, and commercializes True Human monoclonal antibodies for treating various diseases. The company focuses on developing a pipeline of product candidates targeting both inflammatory and infectious diseases. It is also developing interleukin-1 alpha therapies to treat variety of medical conditions, such as cancer, stroke, heart attack, or arthritis; and mediates tissue breakdown, angiogenesis, the formation of blood clots, malaise, muscle wasting, and inflammation. The company was incorporated in 2005 and is headquartered in Austin, Texas.

Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.

XBiotech Inc. has a Value Score of 87, which is considered to be undervalued.

XBiotech Inc.’s price-to-book ratio is higher than its peers. This could make XBiotech Inc. less attractive for value investors when compared to the industry median at 2.04.

You can read more about XBiotech Inc.’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.

Learn More About A+ Investor

Other Biotechnology Stock Grades

Value is just one of the five Stock Grades included in our A+ Investor service. AAII members can see the top-graded stocks—those with grades of A or B for value, growth, momentum, earnings estimate revisions and quality—on the A+ Stock Grades Screener.

Also, if you want full access to all of AAII’s premium services, you can subscribe to one convenient bundled plan called AAII Platinum where you can try out A+ Investor, AAII Dividend Investing, the Stock Superstars Report, Growth Investing and VMQ Stocks. With the other premium services, you can dive deep into additional metrics, portfolios, commentary and information about Biotechnology stocks as well as other industrys.

Choosing Which of the 7 Best Biotechnology Stocks Is Right for You

Choosing which value stocks to invest in will ultimately depend on your individual goals and allocation; however, comparing similar value stocks in the same industry can help you analyze which might be better investments for you in the long run. So, let’s take a look at the Value Grade for all of our stocks.

  • Aadi Bioscience, Inc. stock has a Value Grade of B.
  • Azitra, Inc. stock has a Value Grade of A.
  • HOOKIPA Pharma Inc. stock has a Value Grade of B.
  • Lisata Therapeutics, Inc. stock has a Value Grade of A.
  • Silo Pharma, Inc. stock has a Value Grade of A.
  • Salarius Pharmaceuticals, Inc. stock has a Value Grade of B.
  • XBiotech Inc. stock has a Value Grade of A.

Now that you have a bit more background about each of the 7 undervalued stocks in the Biotechnology industry as well as their overall grades, it’s time for you to conduct additional research to see if these could fit your portfolio needs based on your goals and risk tolerance. AAII can help you figure out both and identify which investments align with what works best for you.

We do so through a program of education that teaches you to invest for yourself and become an effective manager of your own wealth—no more relying on others for your financial independence. You can rely on AAII for timeless articles on financial planning and stock-picking, unbiased research and actionable analysis that makes you a better investor.

A+ Investor adds to that qualitative teaching by giving you a powerful data suite that helps you whittle down investment decisions to find stocks, exchange-traded funds (ETFs) or mutual funds that meet your needs.

Learn More About A+ Investor

Additional Resources About Biotechnology Stocks

Want to learn more about Biotechnology stocks to see if they could be the right investment for you? Check out some additional resources and articles to help you on your financial journey.

AAII Disclaimer

We make no representations or warranties that any investor will, or is likely to, achieve profits similar to those shown, because past, hypothetical or simulated performance is not necessarily indicative of future results. Before making an investment decision, you should consider your circumstances and whether the information on our content is applicable to your situation. This information was prepared in good faith and we accept no liability for any errors or omissions. The full disclaimer can be read here.



Find New Stock Opportunities With Included With AAII Platinum
Zweig Screen: 11.3% Compared to S&P 500
at only 6.9%

Gain Since Inception. Data as of 12/31/2024.




Try AAII Platinum and get full access to
769.3% Stock Superstars Portfolio Total Return Since Inception
Compare to:
710.3% iShare DOW Jones
U.S. Index ETF (IYY)

SSR Group 3 O'Shaughnessy portfolio has a 411.2% gain since inception performance compared to IYY at only 119.1%% Performance as of 11/29/24.

Get your free copy of our special report analyzing the tech stocks most likely to outperform the market.

Download the FREE Report Here:

BECOME A MEMBER FOR ONLY $2

Get access to powerful investment discovery tools and a wealth of investment education to help you achieve your financial goals.