Avoid the stress of overpaying for a stock or missing an opportunity by using the right tools and insights to evaluate Upstream Bio, Inc. before investing.

In this article, we go over a few key elements for understanding Upstream Bio, Inc.’s stock price such as:

• Upstream Bio, Inc.’s current stock price and volume
• Why Upstream Bio, Inc.’s stock price changed recently
• Upgrades and downgrades for UPB from analysts
• UPB’s stock price momentum as measured by its relative strength

About Upstream Bio, Inc. (UPB)

Before we jump into Upstream Bio, Inc.’s stock price, history, target price and what caused it to recently rise, let’s take a look at some background.

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. Its product candidate includes verekitug, which is in Phase 2 clinical development for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps, as well as in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.

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Upstream Bio, Inc.’s Stock Price as of Market Close

As of June 11, 2025, 12:48 PM, CST, Upstream Bio, Inc.’s stock price was $11.710.

Upstream Bio, Inc. is up 1.04% from its previous closing price of $11.590.

During the last market session, Upstream Bio, Inc.’s stock traded between $11.318 and $12.070. Currently, there are approximately 53.62 million shares outstanding for Upstream Bio, Inc..

Upstream Bio, Inc.’s trailing earnings per share are negative, so the stock does not have a meaningful P/E ratio. We suggest investors evaluate other financial metrics to understand its overall valuation.

Upstream Bio, Inc. Stock Price History

Upstream Bio, Inc.’s (UPB) price is currently up 26.87% so far this month.

During the month of June, Upstream Bio, Inc.’s stock price has reached a high of $12.070 and a low of $9.250.

Over the last year, Upstream Bio, Inc. has hit prices as high as $29.460 and as low as $5.140. Year to date, Upstream Bio, Inc.’s stock is down 28.77%.

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What Caused Upstream Bio, Inc. Stock’s Price to Rise?

Stock prices are primarily based on seller supply and buyer demand. But have you ever wondered about what other factors affect a stock's price?

When an analyst changes their opinion of a stock by upgrading or downgrading their rating, it often leads to a sudden stock price adjustment. As of June 10, 2025, there were 2 analysts who downgraded Upstream Bio, Inc.’s stock and 0 analysts who upgraded over the last month.

Additionally, you'll want to evaluate Upstream Bio, Inc.’s financial health and valuation. Investors can use AAII's Value Grade, which combines six key valuation metrics like P/E and P/S ratios for a comprehensive analysis to conduct analysis on Upstream Bio, Inc.’s valuation and financial health. This approach mitigates the limitations of single-metric evaluations.

Upstream Bio, Inc.’s current valuation based on AAII’s Value Grade is a D, which means it is considered to be Expensive.

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Lastly, news and media coverage as well as recent press reports about the company or its industry may cause stock prices to fluctuate. You can check out the most recent news articles about Upstream Bio, Inc. (UPB) by visiting AAII Stock Evaluator.

Relative Price Strength of Upstream Bio, Inc.

Relative price strength measures a stock's performance against the market, helping investors identify stocks that are outperforming benchmarks.

For AAII’s Momentum Grade, a weighted relative price strength is calculated. Follow this link to learn more about the Momentum Grade.

As of June 10, 2025, Upstream Bio, Inc. has a weighted four-quarter relative price strength of %, which translates to a Momentum Score of and is considered to be NA.

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Upstream Bio, Inc. Stock Price: Bottom Line

As of June 11, 2025, Upstream Bio, Inc.’s stock price is $11.710, which is up 1.04% from its previous closing price.

AAII advises against making stock decisions based solely on price or past returns. Instead, consider a variety of metrics, fundamentals, and analytics to evaluate a stock like Upstream Bio, Inc. stock prices are influenced by market supply and demand and offer just a snapshot of a company's overall health.

Subscribing to AAII's A+ Investor provides access to comprehensive analytics and insights for confident investing.