Avoid the stress of overpaying for a stock or missing an opportunity by using the right tools and insights to evaluate OPKO Health, Inc. before investing.

In this article, we go over a few key elements for understanding OPKO Health, Inc.’s stock price such as:

• OPKO Health, Inc.’s current stock price and volume
• Why OPKO Health, Inc.’s stock price changed recently
• Upgrades and downgrades for OPK from analysts
• OPK’s stock price momentum as measured by its relative strength

About OPKO Health, Inc. (OPK)

Before we jump into OPKO Health, Inc.’s stock price, history, target price and what caused it to recently rise, let’s take a look at some background.

OPKO Health, Inc., a healthcare company, engages in the diagnostics and pharmaceuticals businesses in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company’s Diagnostics segment operates BioReference Laboratories that offer laboratory testing services for the detection, diagnosis, evaluation, monitoring, and treatment of diseases, including esoteric testing, molecular diagnostics, anatomical pathology, genetics, women’s health, and correctional healthcare to physician offices, clinics, hospitals, employers, and governmental units; and 4Kscore prostate cancer test services. Its Pharmaceutical segment offers Rayaldee to treat secondary hyperparathyroidism in adults with stage 3 or 4 chronic kidney disease, and vitamin D insufficiency. This segment also develops multi-specific immune therapies focused on oncology, immunology, and infectious diseases; OPK88004, an orally administered selective androgen receptor modulator; OPK88003, a once-weekly administered peptide for the treatment of type 2 diabetes and related obesity; Somatrogon (hGH-CTP), a once-weekly human growth hormone injection; and Factor VIIa-CTP, a novel long-acting coagulation factor to treat hemophilia. In addition, it develops and commercializes longer-acting proprietary versions of already approved therapeutic proteins or peptides; develops and produces specialty APIs; develops, manufactures, markets, and sells pharmaceutical, nutraceutical, veterinary, and ophthalmic products; commercializes food supplements and over the counter products; manufactures and sells products primarily in the generics market; and markets, distributes, and sells pharmaceutical products for a range of indications, including cardiovascular products, vaccines, antibiotics, gastro-intestinal products, hormones, and others. The company also operates pharmaceutical platforms in Spain, Ireland, Chile, and Mexico. OPKO Health, Inc. was founded in 2007 and is headquartered in Miami, Florida.

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OPKO Health, Inc.’s Stock Price as of Market Close

As of January 16, 2026, 9:30 AM, CST, OPKO Health, Inc.’s stock price was $1.290.

OPKO Health, Inc. is up 0.77% from its previous closing price of $1.280.

During the last market session, OPKO Health, Inc.’s stock traded between $1.280 and $1.300. Currently, there are approximately 777.15 million shares outstanding for OPKO Health, Inc..

OPKO Health, Inc.’s trailing earnings per share are negative, so the stock does not have a meaningful P/E ratio. We suggest investors evaluate other financial metrics to understand its overall valuation.

OPKO Health, Inc. Stock Price History

OPKO Health, Inc.’s (OPK) price is currently up 2.37% so far this month.

During the month of January, OPKO Health, Inc.’s stock price has reached a high of $1.380 and a low of $1.240.

Over the last year, OPKO Health, Inc. has hit prices as high as $2.035 and as low as $1.110. Year to date, OPKO Health, Inc.’s stock is up 2.37%.

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What Caused OPKO Health, Inc. Stock’s Price to Rise?

Stock prices are primarily based on seller supply and buyer demand. But have you ever wondered about what other factors affect a stock's price?

When an analyst changes their opinion of a stock by upgrading or downgrading their rating, it often leads to a sudden stock price adjustment. As of January 15, 2026, there was 1 analyst who downgraded OPKO Health, Inc.’s stock and 0 analysts who upgraded over the last month.

Additionally, you'll want to evaluate OPKO Health, Inc.’s financial health and valuation. Investors can use AAII's Value Grade, which combines six key valuation metrics like P/E and P/S ratios for a comprehensive analysis to conduct analysis on OPKO Health, Inc.’s valuation and financial health. This approach mitigates the limitations of single-metric evaluations.

OPKO Health, Inc.’s current valuation based on AAII’s Value Grade is a D, which means it is considered to be Expensive.

Learn how to evaluate stocks with AAII Grades and Scores with A+ Investor today.

Lastly, news and media coverage as well as recent press reports about the company or its industry may cause stock prices to fluctuate. You can check out the most recent news articles about OPKO Health, Inc. (OPK) by visiting AAII Stock Evaluator.

Relative Price Strength of OPKO Health, Inc.

Relative price strength measures a stock's performance against the market, helping investors identify stocks that are outperforming benchmarks.

For AAII’s Momentum Grade, a weighted relative price strength is calculated. Follow this link to learn more about the Momentum Grade.

As of January 15, 2026, OPKO Health, Inc. has a weighted four-quarter relative price strength of -8.59%, which translates to a Momentum Score of 23 and is considered to be Weak.

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OPKO Health, Inc. Stock Price: Bottom Line

As of January 16, 2026, OPKO Health, Inc.’s stock price is $1.290, which is up 0.77% from its previous closing price.

AAII advises against making stock decisions based solely on price or past returns. Instead, consider a variety of metrics, fundamentals, and analytics to evaluate a stock like OPKO Health, Inc. stock prices are influenced by market supply and demand and offer just a snapshot of a company's overall health.

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