Based on key financial metrics such as the price-to-sales ratio, shareholder yield and the price-earnings ratio, the following 4 stocks made the list for top value stocks in the Biotechnology & Medical Research industry. Those looking for value stocks to add to their portfolio may want to use this list as a starting point for further investment research.
Latest Biotechnology & Medical Research Stock News
Before choosing which top Biotechnology & Medical Research stock to buy, be sure to conduct proper due diligence: analyze various financial metrics and look at historical data, public statements and news coverage.
The Biotechnology and Medical Research sub-industry has a positive outlook, a historically defensive sub-industry. Drug sales are anticipated to have high growth, primarily driven by COVID-19 therapeutics, the continued adoption of many new and innovative therapies, a favorable M&A environment, and a low prevalence of patent expirations in 2022. Additionally, companies could see prescription growth pick up as in-person physician visits return to pre-pandemic levels. As COVID-19 variants have emerged, vaccine boosters have been offered in order to increase efficacy. Due to this, repeat vaccinations will likely be necessary for lifelong immunity which would provide a long-lasting and significant source of revenue for lead vaccine developers. Aside from vaccines, the biotech industry is dependent on the volume of new therapy approvals. The FDA’s heavy focus on COVID-19 could slow the approvals on non-COVID-19 therapies. Despite this, the biotech industry will likely see promising sales growth over the next five years as it usually takes at least five years for new drugs to reach peak sales levels. Approval activity has also been on the rise recently. Mergers and acquisitions activity is expected to remain low as a more activist Federal Trade Commission (led by Lina Khan) could be more skeptical of proposed mergers. Year to date through June 30, the S&P 1500 Biotech Index was down 1.6%, vs. a 20.5% decline for the S&P 1500 Composite Index. In 2021, the Biotech Index rose 8.2%, vs. a 26.7% gain for the Composite Index.
Why Focus on Undervalued Biotechnology & Medical Research Stocks?
Value investors seek to buy stocks at a discount to their intrinsic value. Long-term returns show that such strategies are advantageous. Value stocks, as a group, tend to outperform growth stocks over extended periods of time. Typically, value investors perform financial analysis of numerous metrics, don’t follow the herd and are long-term investors.
AAII’s A+ Investor Value Grade is derived from a stock’s Value Score. The Value Score is the percentile rank of the average of the percentile ranks of the price-to-sales ratio, price-earnings ratio, enterprise-value-to-EBITDA (EV/EBITDA) ratio, shareholder yield, price-to-book-value ratio and price-to-free-cash-flow ratio. The score is variable, meaning it can consider all six ratios or, should any of the six ratios not be valid, the remaining ratios that are valid. To be assigned a Value Score, stocks must have a valid (non-null) ratio and corresponding ranking for at least two of the six valuation ratios.
What Goes Into AAII’s Value Grade?
Stock evaluation requires access to huge amounts of data as well as the knowledge and time to sift through it all, make sense of financial ratios, read income statements and analyze recent stock movement. AAII created A+ Investor, a robust data suite that condenses data research in an actionable and customizable way suitable for investors of all knowledge levels, to help investors with that task.
AAII’s proprietary stock grades come with A+ Investor. These offer intuitive A–F grades for more than just value. It is possible for a stock to appear cheap based on one valuation metric but appear expensive on another. It is also possible for one valuation ratio to be associated with outperforming stocks during certain periods of time but not others. Some stocks may even have null values for certain metrics like the price-earnings ratio or the price-to-book ratio but not others. An example of this would be a company with losses instead of profits or a negative book value because of heavy borrowing. Negative earnings or book value result in non-meaningful ratios that are left blank or null.
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4 Undervalued Biotechnology & Medical Research Stocks
Of course, there are countless value stocks that are worth mentioning, but this is a concise list of the top 4 undervalued stocks in the Biotechnology & Medical Research industry for Friday, August 18, 2023. Let’s take a closer look at their individual scores to see how they measure up against each other and the Biotechnology & Medical Research industry median.
| Company | Ticker | Price/Sales | Price/Earnings | EV/EBITDA | Shareholder Yield | Price/Book Value | Price/Free Cash Flow | Value Grade |
| Chimerix Inc | CMRX | 2.53 | 0.5 | na | (1.3%) | 0.38 | na | B |
| Frequency Therapeutics Inc | FREQ | na | na | 0.4 | (2.4%) | 0.50 | na | A |
| LAVA Therapeutics NV | LVTX | 2.42 | na | 1.4 | (2.0%) | 0.63 | na | B |
| Synaptogenix Inc | SNPX | na | na | 1.5 | (5.8%) | 0.19 | na | A |
The Value Grade is assigned based on how each stock’s composite valuation compares to all other stocks.
The process for assigning grades starts with each variable for a given stock. The percentile rankings for all valid ratios that a stock has are calculated. So, for instance, a stock could have a price-to-book ranking in the 43rd percentile, a price-earnings ranking in the 67th percentile, a price-to-sales ranking in the 23rd percentile, etc. Then, those rankings are averaged for each stock. (A minimum of two valid variables are required, though all six will be used if available.)
Once the average of the individual variables is calculated, that average is ranked against all stocks. Put another way, each stock’s composite valuation is compared to all other stocks. These ranks are then sorted into quintiles from the cheapest 20% (a grade of A) to the most expensive 20% (a grade of F).
As always, we recommend that you conduct proper due diligence and research before investing in any security. We also suggest that investors utilize numerous grades, not just value, when it comes to deciding whether a company is a good fit for their allocation needs.
Chimerix Inc’s Value Grade
Value Grade:
| Metric | Score | CMRX | Industry Median |
| Price/Sales | 65 | 2.53 | 8.57 |
| Price/Earnings | 0 | 0.5 | 12.9 |
| EV/EBITDA | na | na | 0.8 |
| Shareholder Yield | 61 | (1.3%) | (7.1%) |
| Price/Book Value | 7 | 0.38 | 1.56 |
| Price/Free Cash Flow | na | na | 21.8 |
Chimerix, Inc. is a biotechnology company. The Company is focused on developing medicines that address unmet medical needs. The Company's product Imipridones is a cancer therapy that provides ONC201, which is in clinical-stage development for H3 K27M-mutant glioma as its lead indication. In addition, imipridone ONC206 is in dose-escalating clinical trials. Imipridones target specific G protein-coupled receptors (GPCRs) and mitochondrial caseinolytic protease P (ClpP), resulting in cancer cell death. The Company's product Imipridone chemical scaffold provides an opportunity to target GPCRs and ClpP with tunable specificity and modality, which enables therapeutic use for cancer and other diseases. Its ONC206 is an imipridone, Dopamine Receptor D2 (DRD2) antagonist and ClpP agonist. Its ONC212 is an imipridone, an investigational agonist of the orphan GPCR tumor suppressor GPR132, as well as ClpP. Its CMX521 is a nucleoside analog antiviral drug candidate for the treatment of SARS-CoV-2.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Chimerix Inc has a Value Score of 77, which is considered to be undervalued.
When you look at Chimerix Inc’s price-to-sales ratio at 2.53 compared to the industry median at 8.57, this company has a lower price relative to revenue compared to its peers. This could make Chimerix Inc’s stock more attractive for value investors.
Chimerix Inc’s price-earnings ratio is 0.47 compared to the industry median at 12.90. This means it has a lower share price relative to earnings compared to its peers. This could make Chimerix Inc more attractive for value investors.
Shareholder yield is the sum of a stock’s dividend yield (paid over previous 12 months minus special dividends) and the percentage of net share buybacks over the previous 12 months. Chimerix Inc’s shareholder yield is higher than its industry median ratio of (7.06%). Value investors may look for an attractive shareholder yield because it can be a powerful tool for identifying if the company has a good management team.
As one of the most common value metrics, the price-to-book ratio evaluates a company’s current market price relative to its book value. Chimerix Inc’s price-to-book ratio is lower than its industry median ratio of 1.56. This could make Chimerix Inc more attractive to investors looking for a new addition to their portfolio.
Frequency Therapeutics Inc’s Value Grade
Value Grade:
| Metric | Score | FREQ | Industry Median |
| Price/Sales | na | na | 8.57 |
| Price/Earnings | na | na | 12.9 |
| EV/EBITDA | 2 | 0.4 | 0.8 |
| Shareholder Yield | 68 | (2.4%) | (7.1%) |
| Price/Book Value | 10 | 0.50 | 1.56 |
| Price/Free Cash Flow | na | na | 21.8 |
Frequency Therapeutics, Inc. is a preclinical-stage regenerative medicine company, which is focused on the development of therapeutics to activate a person’s innate regenerative potential to restore function. The Company, using its progenitor cell activation (PCA) platform, is developing its lead product candidate, FX-322, for the treatment of sensorineural hearing loss (SNHL). FX-322 is designed to treat the underlying cause of SNHL by regenerating hair cells through activation of progenitor cells already present in the cochlea. The Company is also conducting Phase IIb study for the product FX-322. The Company’s SNHL investigational therapeutic program, FX-345, is designed to achieve broader exposure through the cochlea. The Company’s progenitor cell activation (PCA) uses small molecules to activate progenitor cells within the body to create functional tissue.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Frequency Therapeutics Inc has a Value Score of 88, which is considered to be undervalued.
Frequency Therapeutics Inc’s price-to-book ratio is higher than its peers. This could make Frequency Therapeutics Inc less attractive for value investors when compared to the industry median at 1.56.
You can read more about Frequency Therapeutics Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
LAVA Therapeutics NV’s Value Grade
Value Grade:
| Metric | Score | LVTX | Industry Median |
| Price/Sales | 63 | 2.42 | 8.57 |
| Price/Earnings | na | na | 12.9 |
| EV/EBITDA | 5 | 1.4 | 0.8 |
| Shareholder Yield | 66 | (2.0%) | (7.1%) |
| Price/Book Value | 14 | 0.63 | 1.56 |
| Price/Free Cash Flow | na | na | 21.8 |
LAVA Therapeutics NV, formerly known as Lava Therapeutics BV, is a provider of biotechnology research and development services based in the Netherlands. The Company focuses of developing next generation Vdelta T cell engaging bispecific antibodies to fight cancer.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
LAVA Therapeutics NV has a Value Score of 70, which is considered to be undervalued.
LAVA Therapeutics NV’s price-to-book ratio is higher than its peers. This could make LAVA Therapeutics NV less attractive for value investors when compared to the industry median at 1.56.
You can read more about LAVA Therapeutics NV’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Synaptogenix Inc’s Value Grade
Value Grade:
| Metric | Score | SNPX | Industry Median |
| Price/Sales | na | na | 8.57 |
| Price/Earnings | na | na | 12.9 |
| EV/EBITDA | 5 | 1.5 | 0.8 |
| Shareholder Yield | 77 | (5.8%) | (7.1%) |
| Price/Book Value | 2 | 0.19 | 1.56 |
| Price/Free Cash Flow | na | na | 21.8 |
Synaptogenix, Inc. is a biopharmaceutical company. The Company is principally focused on developing therapeutics for patients with neurodegenerative diseases and developmental disorders. The Company is focused on developing a product platform based on a drug candidate called Bryostatin-1, which is synthesized from a natural product (bryostatin) that is isolated from a marine invertebrate organism, for the treatment of Alzheimer's disease (AD). Bryostatin-1 is a Protein Kinase C Epsilon (PKC e), a and e activator that was originally developed as a potential anticancer drug. The Company is evaluating therapeutic applications of bryostatin for other neurodegenerative or cognitive diseases and dysfunctions, such as Fragile X syndrome, Multiple Sclerosis (MS), and Niemann-Pick Type C disease.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Synaptogenix Inc has a Value Score of 86, which is considered to be undervalued.
Synaptogenix Inc’s price-to-book ratio is higher than its peers. This could make Synaptogenix Inc less attractive for value investors when compared to the industry median at 1.56.
You can read more about Synaptogenix Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Other Biotechnology & Medical Research Stock Grades
Value is just one of the five Stock Grades included in our A+ Investor service. AAII members can see the top-graded stocks—those with grades of A or B for value, growth, momentum, earnings estimate revisions and quality—on the A+ Stock Grades Screener.
Also, if you want full access to all of AAII’s premium services, you can subscribe to one convenient bundled plan called AAII Platinum where you can try out A+ Investor, AAII Dividend Investing, the Stock Superstars Report, Growth Investing and VMQ Stocks. With the other premium services, you can dive deep into additional metrics, portfolios, commentary and information about Biotechnology & Medical Research stocks as well as other industrys.
Choosing Which of the 4 Best Biotechnology & Medical Research Stocks Is Right for You
Choosing which value stocks to invest in will ultimately depend on your individual goals and allocation; however, comparing similar value stocks in the same industry can help you analyze which might be better investments for you in the long run. So, let’s take a look at the Value Grade for all of our stocks.
- Chimerix Inc stock has a Value Grade of B.
- Frequency Therapeutics Inc stock has a Value Grade of A.
- LAVA Therapeutics NV stock has a Value Grade of B.
- Synaptogenix Inc stock has a Value Grade of A.
Now that you have a bit more background about each of the 4 undervalued stocks in the Biotechnology & Medical Research industry as well as their overall grades, it’s time for you to conduct additional research to see if these could fit your portfolio needs based on your goals and risk tolerance. AAII can help you figure out both and identify which investments align with what works best for you.
We do so through a program of education that teaches you to invest for yourself and become an effective manager of your own wealth—no more relying on others for your financial independence. You can rely on AAII for timeless articles on financial planning and stock-picking, unbiased research and actionable analysis that makes you a better investor.
A+ Investor adds to that qualitative teaching by giving you a powerful data suite that helps you whittle down investment decisions to find stocks, exchange-traded funds (ETFs) or mutual funds that meet your needs.
Additional Resources About Biotechnology & Medical Research Stocks
Want to learn more about Biotechnology & Medical Research stocks to see if they could be the right investment for you? Check out some additional resources and articles to help you on your financial journey.
- 4 Undervalued Biotechnology & Medical Research Stocks for Friday, August 18
- What You Need to Know About Legend Biotech Corp's Q2 Earnings
- 5 Undervalued Biotechnology & Medical Research Stocks for Thursday, August 17
- What You Need to Know About 2Seventy Bio Inc's Q2 Earnings
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