Based on key financial metrics such as the price-to-sales ratio, shareholder yield and the price-earnings ratio, the following 7 stocks made the list for top value stocks in the Biotechnology & Medical Research industry. Those looking for value stocks to add to their portfolio may want to use this list as a starting point for further investment research.
Latest Biotechnology & Medical Research Stock News
Before choosing which top Biotechnology & Medical Research stock to buy, be sure to conduct proper due diligence: analyze various financial metrics and look at historical data, public statements and news coverage.
The Biotechnology and Medical Research sub-industry has a positive outlook, a historically defensive sub-industry. Drug sales are anticipated to have high growth, primarily driven by COVID-19 therapeutics, the continued adoption of many new and innovative therapies, a favorable M&A environment, and a low prevalence of patent expirations in 2022. Additionally, companies could see prescription growth pick up as in-person physician visits return to pre-pandemic levels. As COVID-19 variants have emerged, vaccine boosters have been offered in order to increase efficacy. Due to this, repeat vaccinations will likely be necessary for lifelong immunity which would provide a long-lasting and significant source of revenue for lead vaccine developers. Aside from vaccines, the biotech industry is dependent on the volume of new therapy approvals. The FDA’s heavy focus on COVID-19 could slow the approvals on non-COVID-19 therapies. Despite this, the biotech industry will likely see promising sales growth over the next five years as it usually takes at least five years for new drugs to reach peak sales levels. Approval activity has also been on the rise recently. Mergers and acquisitions activity is expected to remain low as a more activist Federal Trade Commission (led by Lina Khan) could be more skeptical of proposed mergers. Year to date through June 30, the S&P 1500 Biotech Index was down 1.6%, vs. a 20.5% decline for the S&P 1500 Composite Index. In 2021, the Biotech Index rose 8.2%, vs. a 26.7% gain for the Composite Index.
Why Focus on Undervalued Biotechnology & Medical Research Stocks?
Value investors seek to buy stocks at a discount to their intrinsic value. Long-term returns show that such strategies are advantageous. Value stocks, as a group, tend to outperform growth stocks over extended periods of time. Typically, value investors perform financial analysis of numerous metrics, don’t follow the herd and are long-term investors.
AAII’s A+ Investor Value Grade is derived from a stock’s Value Score. The Value Score is the percentile rank of the average of the percentile ranks of the price-to-sales ratio, price-earnings ratio, enterprise-value-to-EBITDA (EV/EBITDA) ratio, shareholder yield, price-to-book-value ratio and price-to-free-cash-flow ratio. The score is variable, meaning it can consider all six ratios or, should any of the six ratios not be valid, the remaining ratios that are valid. To be assigned a Value Score, stocks must have a valid (non-null) ratio and corresponding ranking for at least two of the six valuation ratios.
What Goes Into AAII’s Value Grade?
Stock evaluation requires access to huge amounts of data as well as the knowledge and time to sift through it all, make sense of financial ratios, read income statements and analyze recent stock movement. AAII created A+ Investor, a robust data suite that condenses data research in an actionable and customizable way suitable for investors of all knowledge levels, to help investors with that task.
AAII’s proprietary stock grades come with A+ Investor. These offer intuitive A–F grades for more than just value. It is possible for a stock to appear cheap based on one valuation metric but appear expensive on another. It is also possible for one valuation ratio to be associated with outperforming stocks during certain periods of time but not others. Some stocks may even have null values for certain metrics like the price-earnings ratio or the price-to-book ratio but not others. An example of this would be a company with losses instead of profits or a negative book value because of heavy borrowing. Negative earnings or book value result in non-meaningful ratios that are left blank or null.
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7 Undervalued Biotechnology & Medical Research Stocks
Of course, there are countless value stocks that are worth mentioning, but this is a concise list of the top 7 undervalued stocks in the Biotechnology & Medical Research industry for Monday, August 28, 2023. Let’s take a closer look at their individual scores to see how they measure up against each other and the Biotechnology & Medical Research industry median.
| Company | Ticker | Price/Sales | Price/Earnings | EV/EBITDA | Shareholder Yield | Price/Book Value | Price/Free Cash Flow | Value Grade |
| Avrobio Inc | AVRO | na | na | 0.9 | (1.0%) | 0.55 | na | A |
| Bellerophon Therapeutics Inc | BLPH | 0.89 | na | 0.2 | (28.1%) | 0.89 | na | B |
| Clearmind Medicine Inc | CMND | na | na | 0.6 | (186.3%) | 0.33 | na | B |
| Lumos Pharma Inc | LUMO | 11.00 | na | 0.3 | 2.4% | 0.56 | na | B |
| Erytech Pharma SA (ADR) | PHXM | 2.27 | na | 0.6 | (26.4%) | 0.64 | na | B |
| Spero Therapeutics Inc | SPRO | 1.24 | na | 0.1 | (59.4%) | 1.23 | 4.5 | B |
| Talis Biomedical Corp | TLIS | 4.01 | na | 1.3 | (1.3%) | 0.10 | na | B |
The Value Grade is assigned based on how each stock’s composite valuation compares to all other stocks.
The process for assigning grades starts with each variable for a given stock. The percentile rankings for all valid ratios that a stock has are calculated. So, for instance, a stock could have a price-to-book ranking in the 43rd percentile, a price-earnings ranking in the 67th percentile, a price-to-sales ranking in the 23rd percentile, etc. Then, those rankings are averaged for each stock. (A minimum of two valid variables are required, though all six will be used if available.)
Once the average of the individual variables is calculated, that average is ranked against all stocks. Put another way, each stock’s composite valuation is compared to all other stocks. These ranks are then sorted into quintiles from the cheapest 20% (a grade of A) to the most expensive 20% (a grade of F).
As always, we recommend that you conduct proper due diligence and research before investing in any security. We also suggest that investors utilize numerous grades, not just value, when it comes to deciding whether a company is a good fit for their allocation needs.
Avrobio Inc’s Value Grade
Value Grade:
| Metric | Score | AVRO | Industry Median |
| Price/Sales | na | na | 8.50 |
| Price/Earnings | na | na | 17.4 |
| EV/EBITDA | 4 | 0.9 | 0.9 |
| Shareholder Yield | 59 | (1.0%) | (7.4%) |
| Price/Book Value | 11 | 0.55 | 1.56 |
| Price/Free Cash Flow | na | na | 20.7 |
AVROBIO, Inc. is a clinical-stage gene therapy company. The Company is focused on developing curative ex vivo lentiviral-based gene therapies to treat patients with rare diseases following a single dose treatment regimen. Its gene therapies employ hematopoietic stem cells that are harvested from the patient and then modified with a lentiviral vector to insert the equivalent of a functional copy of the gene that is mutated in the target disease. The Company is focusing on a group of rare genetic diseases referred to as lysosomal disorders, primarily managed with enzyme replacement therapies. Its pipeline is comprised of various HSC gene therapy programs, which include AVR-RD-02 for the treatment of Gaucher disease type 1 and type 3; AVR-RD-05 for the treatment of neuronopathic mucopolysaccharidosis type II (MPS-II) or Hunter syndrome; and AVR-RD-03 for the treatment of Pompe disease.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Avrobio Inc has a Value Score of 91, which is considered to be undervalued.
Now, let’s assess Avrobio Inc’s EV/EBITDA ratio, also known as enterprise multiple. At 0.9, when compared to the industry median of 0.9, the company may be considered overvalued in relation to its peers. Value investors could use the enterprise multiple to identify stocks that are considered overvalued or undervalued relative to their industry.
Shareholder yield is the sum of a stock’s dividend yield (paid over previous 12 months minus special dividends) and the percentage of net share buybacks over the previous 12 months. Avrobio Inc’s shareholder yield is higher than its industry median ratio of (7.45%). Value investors may look for an attractive shareholder yield because it can be a powerful tool for identifying if the company has a good management team.
As one of the most common value metrics, the price-to-book ratio evaluates a company’s current market price relative to its book value. Avrobio Inc’s price-to-book ratio is lower than its industry median ratio of 1.56. This could make Avrobio Inc more attractive to investors looking for a new addition to their portfolio.
Bellerophon Therapeutics Inc’s Value Grade
Value Grade:
| Metric | Score | BLPH | Industry Median |
| Price/Sales | 32 | 0.89 | 8.50 |
| Price/Earnings | na | na | 17.4 |
| EV/EBITDA | 0 | 0.2 | 0.9 |
| Shareholder Yield | 89 | (28.1%) | (7.4%) |
| Price/Book Value | 25 | 0.89 | 1.56 |
| Price/Free Cash Flow | na | na | 20.7 |
Bellerophon Therapeutics, Inc. is a clinical-stage therapeutics company. The Company is focused on developing products that address significant unmet medical needs in the treatment of cardiopulmonary diseases. The Company?s focus is to develop its nitric oxide therapy for patients with pulmonary hypertension (PH) using its delivery system, INOpulse. The Company?s INOpulse program is an extension of the technology used in hospitals to deliver continuous flow inhaled nitric oxide. INOpulse program is built on scientific and technical development for the therapeutic delivery of inhaled nitric oxide. It is also developing INOpulse for the treatment of patients with fibrotic interstitial lung disease (fILD), PH-Sarcoidosis, PH-chronic obstructive pulmonary disease (COPD), pulmonary arterial hypertension, and other pulmonary hypertension conditions. The Company?s subsidiaries include Bellerophon BCM LLC, Bellerophon Pulse Technologies LLC and Bellerophon Services, Inc.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Bellerophon Therapeutics Inc has a Value Score of 71, which is considered to be undervalued.
Bellerophon Therapeutics Inc’s price-to-book ratio is higher than its peers. This could make Bellerophon Therapeutics Inc less attractive for value investors when compared to the industry median at 1.56.
You can read more about Bellerophon Therapeutics Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Clearmind Medicine Inc’s Value Grade
Value Grade:
| Metric | Score | CMND | Industry Median |
| Price/Sales | na | na | 8.50 |
| Price/Earnings | na | na | 17.4 |
| EV/EBITDA | 3 | 0.6 | 0.9 |
| Shareholder Yield | 97 | (186.3%) | (7.4%) |
| Price/Book Value | 5 | 0.33 | 1.56 |
| Price/Free Cash Flow | na | na | 20.7 |
Clearmind Medicine Inc. is a Canada-based psychedelic pharmaceutical biotech company, which is focused on the discovery and development of psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorder. The Company is engaged in the research and development of compounds derived from psychedelics and commercializes them as regulated medicines, foods or supplements.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Clearmind Medicine Inc has a Value Score of 74, which is considered to be undervalued.
Clearmind Medicine Inc’s price-to-book ratio is higher than its peers. This could make Clearmind Medicine Inc less attractive for value investors when compared to the industry median at 1.56.
You can read more about Clearmind Medicine Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Lumos Pharma Inc’s Value Grade
Value Grade:
| Metric | Score | LUMO | Industry Median |
| Price/Sales | 91 | 11.00 | 8.50 |
| Price/Earnings | na | na | 17.4 |
| EV/EBITDA | 2 | 0.3 | 0.9 |
| Shareholder Yield | 31 | 2.4% | (7.4%) |
| Price/Book Value | 11 | 0.56 | 1.56 |
| Price/Free Cash Flow | na | na | 20.7 |
Lumos Pharma, Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in advancing its clinical program and focused on identifying, acquiring, developing, and commercializing products and new therapies for people with rare diseases. Its pipeline is focused on the development of an orally administered small molecule, LUM-201, which is a growth hormone (GH) secretagogue, also called ibutamoren, for rare endocrine disorders that require injectable recombinant human growth hormone (rhGH). LUM-201 is a tablet formulation that is intended to be administered once daily. LUM-201 stimulates GH via the GH secretagogue receptor (GHSR1a), also known as the ghrelin receptor, and also suppresses the release of somatostatin, thus providing a differentiated mechanism of action to treat some rare endocrine disorders (involving a deficiency of GH) by increasing the amplitude of endogenous, pulsatile GH secretion. Lumos Pharma Sub, Inc. (Private Lumos) is its subsidiary.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Lumos Pharma Inc has a Value Score of 76, which is considered to be undervalued.
Lumos Pharma Inc’s price-to-book ratio is higher than its peers. This could make Lumos Pharma Inc less attractive for value investors when compared to the industry median at 1.56.
You can read more about Lumos Pharma Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Erytech Pharma SA (ADR)’s Value Grade
Value Grade:
| Metric | Score | PHXM | Industry Median |
| Price/Sales | 61 | 2.27 | 8.50 |
| Price/Earnings | na | na | 17.4 |
| EV/EBITDA | 3 | 0.6 | 0.9 |
| Shareholder Yield | 88 | (26.4%) | (7.4%) |
| Price/Book Value | 15 | 0.64 | 1.56 |
| Price/Free Cash Flow | na | na | 20.7 |
PHAXIAM Therapeutics SA, formerly known as ERYTECH PHARMA SA, is a France-based biopharmaceutical company developing medicinal products mainly in oncology, hematology and immunology fields of business. The company relies on the use of phages, natural bacteria-killing viruses. PHAXIAM Therapeutics SA is developing a portfolio of phages targeting three of the most resistant and dangerous bacteria, which alone account for more than two-thirds of resistant nosocomial infections: Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. It offers ESY-ASP (GRASPA), a medicinal product consisting of L-Asparaginase entrapped into human homologous red blood cells. The product is used for treatment of Acute Lymphoblastic Leukemia (ALL), a childhood cancer.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Erytech Pharma SA (ADR) has a Value Score of 62, which is considered to be undervalued.
Erytech Pharma SA (ADR)’s price-to-book ratio is higher than its peers. This could make Erytech Pharma SA (ADR) less attractive for value investors when compared to the industry median at 1.56.
You can read more about Erytech Pharma SA (ADR)’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Spero Therapeutics Inc’s Value Grade
Value Grade:
| Metric | Score | SPRO | Industry Median |
| Price/Sales | 41 | 1.24 | 8.50 |
| Price/Earnings | na | na | 17.4 |
| EV/EBITDA | 0 | 0.1 | 0.9 |
| Shareholder Yield | 94 | (59.4%) | (7.4%) |
| Price/Book Value | 38 | 1.23 | 1.56 |
| Price/Free Cash Flow | 12 | 4.5 | 20.7 |
Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on identifying, developing, and commercializing treatments involving bacterial infections, including multi-drug resistant (MDR) bacterial infections, and rare diseases where there is unmet medical and patient need. Its lead product candidate, tebipenem pivoxil hydrobromide (tebipenem HBr) is designed to be the oral carbapenem-class antibiotic for use to treat certain bacterial infections that cause complicated urinary tract infections (cUTIs), including pyelonephritis, caused by certain microorganisms, in adult patients who have limited oral treatment options. Its pipeline also includes SPR720 and SPR206. SPR720 is designed to be the oral treatment for non-tuberculous mycobacterial (NTM) infection. SPR206 is a direct acting intravenous (IV)-administered polymyxin analogue developed from its potentiator platform to treat MDR Gram-negative bacterial infections in the hospital setting.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Spero Therapeutics Inc has a Value Score of 70, which is considered to be undervalued.
Spero Therapeutics Inc’s price-to-book ratio is higher than its peers. This could make Spero Therapeutics Inc less attractive for value investors when compared to the industry median at 1.56.
You can read more about Spero Therapeutics Inc’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Talis Biomedical Corp’s Value Grade
Value Grade:
| Metric | Score | TLIS | Industry Median |
| Price/Sales | 76 | 4.01 | 8.50 |
| Price/Earnings | na | na | 17.4 |
| EV/EBITDA | 4 | 1.3 | 0.9 |
| Shareholder Yield | 62 | (1.3%) | (7.4%) |
| Price/Book Value | 1 | 0.10 | 1.56 |
| Price/Free Cash Flow | na | na | 20.7 |
Talis Biomedical Corporation is engaged in transforming diagnostic testing by developing and commercializing products that are designed to enable molecular testing for infectious diseases and other conditions at the point of care. The Company is engaged in developing the Talis One system, a cloud-enabled molecular diagnostic platform. The Talis One system consists of compact instrument, single-use test cartridges and software that is designed to support a central cloud database, which work together and are designed to provide central laboratory levels of accuracy and be operated by an untrained user. It is also focused on developing Talis One assay kits for respiratory infections, and infections related to women's health and sexually transmitted infections (STIs). It is also developing influenza A and influenza B tests to be included as part of a respiratory panel with its COVID-19 assay (Respiratory Panel), as well as exploring adding a respiratory syncytial virus (RSV) test.
Stocks with a Value Score from 81 to 100 are considered deep value, those with a score between 61 and 80 are value and so on.
Talis Biomedical Corp has a Value Score of 72, which is considered to be undervalued.
Talis Biomedical Corp’s price-to-book ratio is higher than its peers. This could make Talis Biomedical Corp less attractive for value investors when compared to the industry median at 1.56.
You can read more about Talis Biomedical Corp’s key financial metrics like shareholder yield, price-to-free-cash-flow and EV/EBITDA ratio, or learn more about its Momentum and Growth Grades, by subscribing to A+ Investor.
Other Biotechnology & Medical Research Stock Grades
Value is just one of the five Stock Grades included in our A+ Investor service. AAII members can see the top-graded stocks—those with grades of A or B for value, growth, momentum, earnings estimate revisions and quality—on the A+ Stock Grades Screener.
Also, if you want full access to all of AAII’s premium services, you can subscribe to one convenient bundled plan called AAII Platinum where you can try out A+ Investor, AAII Dividend Investing, the Stock Superstars Report, Growth Investing and VMQ Stocks. With the other premium services, you can dive deep into additional metrics, portfolios, commentary and information about Biotechnology & Medical Research stocks as well as other industrys.
Choosing Which of the 7 Best Biotechnology & Medical Research Stocks Is Right for You
Choosing which value stocks to invest in will ultimately depend on your individual goals and allocation; however, comparing similar value stocks in the same industry can help you analyze which might be better investments for you in the long run. So, let’s take a look at the Value Grade for all of our stocks.
- Avrobio Inc stock has a Value Grade of A.
- Bellerophon Therapeutics Inc stock has a Value Grade of B.
- Clearmind Medicine Inc stock has a Value Grade of B.
- Lumos Pharma Inc stock has a Value Grade of B.
- Erytech Pharma SA (ADR) stock has a Value Grade of B.
- Spero Therapeutics Inc stock has a Value Grade of B.
- Talis Biomedical Corp stock has a Value Grade of B.
Now that you have a bit more background about each of the 7 undervalued stocks in the Biotechnology & Medical Research industry as well as their overall grades, it’s time for you to conduct additional research to see if these could fit your portfolio needs based on your goals and risk tolerance. AAII can help you figure out both and identify which investments align with what works best for you.
We do so through a program of education that teaches you to invest for yourself and become an effective manager of your own wealth—no more relying on others for your financial independence. You can rely on AAII for timeless articles on financial planning and stock-picking, unbiased research and actionable analysis that makes you a better investor.
A+ Investor adds to that qualitative teaching by giving you a powerful data suite that helps you whittle down investment decisions to find stocks, exchange-traded funds (ETFs) or mutual funds that meet your needs.
Additional Resources About Biotechnology & Medical Research Stocks
Want to learn more about Biotechnology & Medical Research stocks to see if they could be the right investment for you? Check out some additional resources and articles to help you on your financial journey.
- 7 Undervalued Biotechnology & Medical Research Stocks for Monday, August 28
- 3 Undervalued Biotechnology & Medical Research Stocks for Friday, August 25
- Why Arvinas Inc’s (ARVN) Stock Is Up 5.27%
- Why Intercept Pharmaceuticals Inc’s (ICPT) Stock Is Up 4.25%
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